Challenges and strategies of matrix effects using chromatography-mass spectrometry: An overview from research versus regulatory viewpoints
Matrix components of a sample can affect the quantitative measurement of the target
analytes. This singularity is named “matrix effects” and should be considered for method …
analytes. This singularity is named “matrix effects” and should be considered for method …
Performance parameters for analytical method validation: Controversies and discrepancies among numerous guidelines
F Raposo, C Ibelli-Bianco - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
The main objective of method validation process is to prove that an analytical method is
acceptable for its intended purpose. The necessity for laboratories to use fully validated …
acceptable for its intended purpose. The necessity for laboratories to use fully validated …
[HTML][HTML] Factors affecting public transport performance due to the COVID-19 outbreak: A worldwide analysis
In this paper we investigate the public transport trip frequency variations, as well as the
reasons that led to the shift away from public transport means, due to the COVID-19 …
reasons that led to the shift away from public transport means, due to the COVID-19 …
Exploring the link between ultrasonic and strength behavior of cementitious mine backfill by considering pore structure
Understanding the porosity/pore linkage and strength properties of cementitious mine
backfill (CMB) is essential for the design of underground mining filling. Adoption of new …
backfill (CMB) is essential for the design of underground mining filling. Adoption of new …
Mass spectrometry as a quantitative tool in plant metabolomics
TF Jorge, AT Mata, C António - … Transactions of the …, 2016 - royalsocietypublishing.org
Metabolomics is a research field used to acquire comprehensive information on the
composition of a metabolite pool to provide a functional screen of the cellular state. Studies …
composition of a metabolite pool to provide a functional screen of the cellular state. Studies …
Traditional calibration methods in atomic spectrometry and new calibration strategies for inductively coupled plasma mass spectrometry
Applications, advantages, and limitations of the traditional external standard calibration,
matrix-matched calibration, internal standardization, and standard additions, as well as the …
matrix-matched calibration, internal standardization, and standard additions, as well as the …
[HTML][HTML] Validation of analytical methods in a pharmaceutical quality system: An overview focused on HPLC methods
BM Marson, V Concentino, AM Junkert, MM Fachi… - Química …, 2020 - SciELO Brasil
Analytical validation has fundamental importance in the scope of Good Manufacturing
Practice (GMP) for pharmaceutical products since it establishes scientific evidence that an …
Practice (GMP) for pharmaceutical products since it establishes scientific evidence that an …
[HTML][HTML] Advances and applications of capillary electromigration methods in the analysis of therapeutic and diagnostic recombinant proteins–A Review
H Stutz - Journal of Pharmaceutical and Biomedical Analysis, 2023 - Elsevier
This review provides a comprehensive overview of methodological advances and
applications of CE in the analysis and characterization of recombinant therapeutic and …
applications of CE in the analysis and characterization of recombinant therapeutic and …
Suspect and nontarget screening of mycotoxins and their modified forms in wheat products based on ultrahigh-performance liquid chromatography-high resolution …
Y Zhang, T Chen, D Chen, W Liang, X Lu… - … of Chromatography A, 2023 - Elsevier
Various forms of mycotoxins commonly exist in food and pose a significant risk to human
health. Here a comprehensive suspect and nontarget screening strategy for both parent and …
health. Here a comprehensive suspect and nontarget screening strategy for both parent and …
Chemical characterization and non-targeted analysis of medical device extracts: a review of current approaches, gaps, and emerging practices
EM Sussman, B Oktem, IS Isayeva, J Liu… - ACS Biomaterials …, 2022 - ACS Publications
The developers of medical devices evaluate the biocompatibility of their device prior to
FDA's review and subsequent introduction to the market. Chemical characterization …
FDA's review and subsequent introduction to the market. Chemical characterization …