Oxidative stress, inflammation and colorectal cancer: an overview

A Bardelčíková, J Šoltys, J Mojžiš - Antioxidants, 2023 - mdpi.com
Colorectal cancer (CRC) represents the second leading cause of cancer-related deaths
worldwide. The pathogenesis of CRC is a complex multistep process. Among other factors …

Role of Akkermansia in Human Diseases: From Causation to Therapeutic Properties

A Pellegrino, G Coppola, F Santopaolo, A Gasbarrini… - Nutrients, 2023 - mdpi.com
The gut microbiota plays a critical role in the modulation of host metabolism and immune
response, and its impairment has been implicated in many gastrointestinal and …

Microbiome confounders and quantitative profiling challenge predicted microbial targets in colorectal cancer development

RY Tito, S Verbandt, M Aguirre Vazquez, L Lahti… - Nature medicine, 2024 - nature.com
Despite substantial progress in cancer microbiome research, recognized confounders and
advances in absolute microbiome quantification remain underused; this raises concerns …

[HTML][HTML] The communication mechanism of the gut-brain axis and its effect on central nervous system diseases: A systematic review

S Lu, Q Zhao, Y Guan, Z Sun, W Li, S Guo… - Biomedicine & …, 2024 - Elsevier
Gut microbiota is involved in intricate and active metabolic processes the host's brain
function, especially its role in immune responses, secondary metabolism, and symbiotic …

Risk of cancer in patients with inflammatory bowel diseases and keys for patient management

V Laredo, S García-Mateo, SJ Martínez-Domínguez… - Cancers, 2023 - mdpi.com
Simple Summary Inflammatory Bowel Diseases (IBDs) are increasingly prevalent
pathologies due to the rise in incidence in some geographic areas and the improvement in …

Revealing the association between East Asian oral microbiome and colorectal cancer through Mendelian randomization and multi-omics analysis

Y Gu, L Jiang, M Shui, H Luo, X Zhou… - Frontiers in Cellular …, 2024 - frontiersin.org
Background Colorectal cancer (CRC) poses a global health threat, with the oral microbiome
increasingly implicated in its pathogenesis. This study leverages Mendelian Randomization …

Exploring the gut microbiome's role in colorectal cancer: Diagnostic and prognostic implications

G Chen, Q Ren, Z Zhong, Q Li, Z Huang… - Frontiers in …, 2024 - frontiersin.org
The intricate interplay between the gut microbiome and colorectal cancer (CRC) presents
novel avenues for early diagnosis and prognosis, crucial for improving patient outcomes …

Intestinal microbiota and miRNA in IBD: a narrative review about discoveries and perspectives for the future

ECS Oliveira, AEV Quaglio, DO Magro… - International Journal of …, 2023 - mdpi.com
Inflammatory bowel disease (IBD) includes Crohn's disease (CD) and ulcerative colitis (UC)
and comprises a chronic gastrointestinal tract disorder characterized by hyperactive and …

Navigating beyond associations: Opportunities to establish causal relationships between the gut microbiome and colorectal carcinogenesis

FS Baas, N Brusselaers, ID Nagtegaal, L Engstrand… - Cell Host & Microbe, 2024 - cell.com
The gut microbiota has been recognized as an important determinant in the initiation and
progression of colorectal cancer (CRC), with recent studies shining light on the molecular …

[HTML][HTML] Photodynamic therapy for inflammatory and cancerous diseases of the intestines: molecular mechanisms and prospects for application

B Deng, K Wang, L Zhang, Z Qiu, W Dong… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Photodynamic therapy (PDT) is a minimally invasive treatment that effectively targets cancer
and inflammatory diseases. It has gained recognition for its efficacy, low toxicity, and …