In the past year, data about the level and nature of linkage disequilibrium between alleles of
tightly linked SNPs have started to become available. Furthermore, increasing evidence of …

The population of Quebec, Canada (7.3 million) contains∼ 6 million French Canadians;
they are the descendants of∼ 8500 permanent French settlers who colonized Nouvelle …

Inhibition of serotonergic raphe neurons is mediated by somatodendritic 5-HT1A
autoreceptors, which may be increased in depressed patients. We report an association of …

A central goal of population genetics is to understand how genetic drift, natural selection,
and gene flow shape allele frequencies through time. However, the actual processes …

Intergenerational time intervals are frequently used in human population-genetics studies
concerned with the ages and origins of mutations. In most cases, mean intervals of 20 or 25 …

Knowledge of the genetic demography of Quebec is useful for gene map**, diagnosis,
treatment, community genetics and public health. The French‐Canadian population of …

Background One of the enzymes involved in the production of free radicals in atherosclerotic
plaques is myeloperoxidase (MPO). There is a functional G/A polymorphism 463 bp …

We performed extensive and realistic simulations of the colonization process of Europe by
Neolithic farmers, as well as their potential admixture and competition with local Palaeolithic …

SARS-CoV-2 infection causing the novel coronavirus disease 2019 (COVID–19) has been
responsible for more than 2.8 million deaths and nearly 125 million infections worldwide as …

Peroxisome proliferator-activated receptor alpha (PPARα) is a member of the steroid
hormone receptor super family involved in the control of cellular lipid utilization. This makes …