The anti-oxidative, anti-inflammatory, anti-apoptotic, and anti-necroptotic role of zinc in COVID-19 and sepsis
Zinc is a structural component of proteins, functions as a catalytic co-factor in DNA synthesis
and transcription of hundreds of enzymes, and has a regulatory role in protein–DNA …
and transcription of hundreds of enzymes, and has a regulatory role in protein–DNA …
A glimpse into viral warfare: decoding the intriguing role of highly pathogenic coronavirus proteins in apoptosis regulation
L Cheng, Y Rui, Y Wang, S Chen, J Su… - Journal of Biomedical …, 2024 - Springer
Coronaviruses employ various strategies for survival, among which the activation of
endogenous or exogenous apoptosis stands out, with viral proteins playing a pivotal role …
endogenous or exogenous apoptosis stands out, with viral proteins playing a pivotal role …
TRIM7 ubiquitinates SARS-CoV-2 membrane protein to limit apoptosis and viral replication
SARS-CoV-2 is a highly transmissible virus that causes COVID-19 disease. Mechanisms of
viral pathogenesis include excessive inflammation and viral-induced cell death, resulting in …
viral pathogenesis include excessive inflammation and viral-induced cell death, resulting in …
The role of programmed cell death in organ dysfunction induced by opportunistic pathogens
Y Wang, L Weng, X Wu, B Du - Critical Care, 2025 - Springer
Sepsis is a life-threatening condition resulting from pathogen infection and characterized by
organ dysfunction. Programmed cell death (PCD) during sepsis has been associated with …
organ dysfunction. Programmed cell death (PCD) during sepsis has been associated with …
[HTML][HTML] Chromatin Regulator SMARCA4 Is Essential for MHV-Induced Inflammatory Cell Death, PANoptosis
The innate immune system serves as the first line of defense against β-coronaviruses (β-
CoVs), a family of viruses that includes SARS-CoV-2. Viral sensing via pattern recognition …
CoVs), a family of viruses that includes SARS-CoV-2. Viral sensing via pattern recognition …
[HTML][HTML] An integrated bioinformatics approach reveals the potential role of microRNA-30b-5p and let-7a-5p during SARS CoV-2 spike-1 mediated neuroinflammation
P Pawar, K Akolkar, V Saxena - International Journal of Biological …, 2024 - Elsevier
SARS-CoV-2 induced neuroinflammation contributing to neurological sequelae is one of the
critical outcomes of long-COVID, however underlying regulatory mechanisms involved …
critical outcomes of long-COVID, however underlying regulatory mechanisms involved …
Sulfur Dioxide Alleviates Aortic Dissection Through Inhibiting Vascular Smooth Muscle Cell Phenotype Switch, Migration, and Proliferation via miR-184-3p/Cyp26b1 …
J He, K Huang, X Fan, G Chang - Antioxidants & Redox Signaling, 2025 - liebertpub.com
Aims: Abnormal migration and proliferation of vascular smooth muscle cells (VSMCs) are
considered early events in the onset of thoracic aortic dissection (TAD). Endogenous sulfur …
considered early events in the onset of thoracic aortic dissection (TAD). Endogenous sulfur …
Inflammatory response to SARS-CoV 2 and other respiratory viruses
Introduction Lower respiratory tract infections (LRTI) remain a significant global cause of
mortality and disability. Viruses constitute a substantial proportion of LRTI cases, with their …
mortality and disability. Viruses constitute a substantial proportion of LRTI cases, with their …