Periodontal disease (PD) is one of the most common inflammatory oral diseases, affecting
approximately 47% of adults aged 30 years or older in the United States. If not treated …

As a new type of injectable biomaterials, functional microspheres have attracted increasing
attention in tissue regeneration because they possess some advantageous properties …

Functional polymeric micro-/nanofibers have emerged as promising materials for the
construction of structures potentially useful in biomedical fields. Among all kinds of …

Shortcomings related to the treatment of bone diseases and consequent tissue regeneration
such as transplants have been addressed to some extent by tissue engineering and …

Injectable scaffolds are appealing for tissue regeneration because they offer many
advantages over pre-formed scaffolds. This article provides a comprehensive review of the …

Bone repair and regeneration process is markedly impaired in diabetes mellitus (DM) that
affects hundreds of millions of people worldwide. As a chronic inflammatory disease, DM …

The foreign body reaction (FBR) is described as a local chronic inflammation after
implantation of biomaterials in which macrophages involved intimately. At the stage of acute …

Stem cells and tissue-derived stromal cells stimulate the repair of degenerated and injured
tissues, motivating a growing number of cell-based interventions in the musculoskeletal …

The rapid and effective bone regeneration of large non-healing defects remains challenging.
Bioactive proteins, such as bone morphogenetic protein (BMP)-2, are proved their …

The healing of bone defects depends on early revascularization for delivery of oxygen,
nutrients, growth factors, and stem cells to the injury region but also elimination of metabolic …