Synaptic memory and CaMKII
RA Nicoll, H Schulman - Physiological reviews, 2023 - journals.physiology.org
Ca2+/calmodulin-dependent protein kinase II (CaMKII) and long-term potentiation (LTP)
were discovered within a decade of each other and have been inextricably intertwined ever …
were discovered within a decade of each other and have been inextricably intertwined ever …
Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling
RD Burgoyne - Nature Reviews Neuroscience, 2007 - nature.com
In neurons, intracellular calcium signals have crucial roles in activating neurotransmitter
release and in triggering alterations in neuronal function. Calmodulin has been widely …
release and in triggering alterations in neuronal function. Calmodulin has been widely …
[HTML][HTML] The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer
Calmodulin (CaM) is a ubiquitous Ca 2+ receptor protein mediating a large number of
signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …
signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …
Ganoderic acid D prevents oxidative stress‐induced senescence by targeting 14‐3‐3ε to activate CaM/CaMKII/NRF2 signaling pathway in mesenchymal stem cells
H Yuan, Y Xu, Y Luo, JR Zhang, XX Zhu, JH **ao - Aging Cell, 2022 - Wiley Online Library
Stem cell senescence is an important cause of aging. Delaying senescence may present a
novel way to combat aging and age‐associated diseases. This study provided a mechanistic …
novel way to combat aging and age‐associated diseases. This study provided a mechanistic …
[HTML][HTML] VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
T Li, H Zhao, G Guo, S **a, L Wang - Cell Reports, 2023 - cell.com
Consisting of three signaling pathways, the unfolded protein response (UPR) can be either
protective or detrimental to cells that undergo ER stress. Elaborate regulation of the UPR is …
protective or detrimental to cells that undergo ER stress. Elaborate regulation of the UPR is …
Protein–protein interactions with connexin 43: Regulation and function
Connexins are integral membrane building blocks that form gap junctions, enabling direct
cytoplasmic exchange of ions and low-molecular-mass metabolites between adjacent cells …
cytoplasmic exchange of ions and low-molecular-mass metabolites between adjacent cells …
Structure, function and drug discovery of GPCR signaling
L Cheng, F **a, Z Li, C Shen, Z Yang, H Hou… - Molecular …, 2023 - Springer
G protein-coupled receptors (GPCRs) are versatile and vital proteins involved in a wide
array of physiological processes and responses, such as sensory perception (eg, vision …
array of physiological processes and responses, such as sensory perception (eg, vision …
In situ formation of an azo bridge on proteins controllable by visible light
Optical modulation of proteins provides superior spatiotemporal resolution for understanding
biological processes, and photoswitches built on light-sensitive proteins have been …
biological processes, and photoswitches built on light-sensitive proteins have been …
Neurogranin enhances synaptic strength through its interaction with calmodulin
L Zhong, T Cherry, CE Bies, MA Florence… - The EMBO …, 2009 - embopress.org
Learning‐correlated plasticity at CA1 hippocampal excitatory synapses is dependent on
neuronal activity and NMDA receptor (NMDAR) activation. However, the molecular …
neuronal activity and NMDA receptor (NMDAR) activation. However, the molecular …
The role of calmodulin kinase II in myocardial physiology and disease
LF Couchonnal, ME Anderson - Physiology, 2008 - journals.physiology.org
The multifunctional Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates a rich
variety of downstream targets in heart. Ca2+ homeostatic proteins are important CaMKII …
variety of downstream targets in heart. Ca2+ homeostatic proteins are important CaMKII …