2023 ESC Guidelines for the management of cardiomyopathies: Developed by the task force on the management of cardiomyopathies of the European Society of …

E Arbelo, A Protonotarios, JR Gimeno… - European heart …, 2023‏ - academic.oup.com
• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Heart failure in cardiomyopathies: a position paper from the Heart Failure Association of the European Society of Cardiology

PM Seferović, M Polovina, J Bauersachs… - European journal of …, 2019‏ - Wiley Online Library
Cardiomyopathies are a heterogeneous group of heart muscle diseases and an important
cause of heart failure (HF). Current knowledge on incidence, pathophysiology and natural …

Disorders of lysosomal acidification—The emerging role of v-ATPase in aging and neurodegenerative disease

DJ Colacurcio, RA Nixon - Ageing research reviews, 2016‏ - Elsevier
Autophagy and endocytosis deliver unneeded cellular materials to lysosomes for
degradation. Beyond processing cellular waste, lysosomes release metabolites and ions …

The role of autophagy in skeletal muscle diseases

Q **a, X Huang, J Huang, Y Zheng, ME March… - Frontiers in …, 2021‏ - frontiersin.org
Skeletal muscle is the most abundant type of tissue in human body, being involved in
diverse activities and maintaining a finely tuned metabolic balance. Autophagy …

Hydroxychloroquine in rheumatic autoimmune disorders and beyond

EL Nirk, F Reggiori, M Mauthe - EMBO molecular medicine, 2020‏ - embopress.org
Initially used as antimalarial drugs, hydroxychloroquine (HCQ) and, to a lesser extent,
chloroquine (CQ) are currently being used to treat several diseases. Due to its cost …

Cardiomyopathies due to left ventricular noncompaction, mitochondrial and storage diseases, and inborn errors of metabolism

JA Towbin, JL Jefferies - Circulation research, 2017‏ - ahajournals.org
The normal function of the human myocardium requires the proper generation and utilization
of energy and relies on a series of complex metabolic processes to achieve this normal …

Hypertrophic cardiomyopathy in children: pathophysiology, diagnosis, and treatment of non-sarcomeric causes

E Monda, M Rubino, M Lioncino, F Di Fraia… - Frontiers in …, 2021‏ - frontiersin.org
Hypertrophic cardiomyopathy (HCM) is a myocardial disease characterized by left
ventricular hypertrophy not solely explained by abnormal loading conditions. Despite its rare …

[HTML][HTML] Crosstalk between autophagy and apoptosis: potential and emerging therapeutic targets for cardiac diseases

M Li, P Gao, J Zhang - International journal of molecular sciences, 2016‏ - mdpi.com
Autophagy is a cell survival process which is related to breaking down and reusing
cytoplasm components. Moreover, autophagy regulates cell death under certain conditions …

Therapeutic targeting of autophagy in cardiovascular disease

GG Schiattarella, JA Hill - Journal of molecular and cellular cardiology, 2016‏ - Elsevier
Autophagy is an evolutionarily ancient process of intracellular catabolism necessary to
preserve cellular homeostasis in response to a wide variety of stresses. In the case of post …