Transcription factors are involved in a large number of human diseases such as cancers for
which they account for about 20% of all oncogenes identified so far. For long time, with the …

Abstract RNA polymerase II (Pol II) transcribes all protein-coding genes and many
noncoding RNAs in eukaryotic genomes. Although Pol II is a complex, 12-subunit enzyme, it …

INTRODUCTION RNA polymerase II (Pol II)–mediated transcription initiation requires
assembly of a preinitiation complex (PIC), during which the 14-subunit transcription factor IID …

When fully extended, one copy of the three billion base pair human genome reaches a
length of over two meters. Yet, it must be packaged into the nucleus of a cell with an average …

Transcription of eukaryotic protein-coding genes commences with the assembly of a
conserved initiation complex, which consists of RNA polymerase II (Pol II) and the general …

Principles of Nucleic Acid Structure, Second Edition, provides the most complete and
concise summary of underlying principles and approaches to studying nucleic acid structure …

The recognition of specific DNA sequences by proteins is thought to depend on two types of
mechanism: one that involves the formation of hydrogen bonds with specific bases, primarily …

Xanthomonads are bacterial plant pathogens that cause diseases on many plant species,
including important crops. Key to pathogenicity of most Xanthomonas pathovars is a Hrp …

Specific interactions between proteins and DNA are fundamental to many biological
processes. In this review, we provide a revised view of protein-DNA interactions that …

We present a comprehensive software package, 3DNA, for the analysis, reconstruction and
visualization of three‐dimensional nucleic acid structures. Starting from a coordinate file in …