Effectiveness of zebrafish models in understanding human diseases—A review of models

M Adhish, I Manjubala - Heliyon, 2023 - cell.com
Understanding the detailed mechanism behind every human disease, disorder, defect, and
deficiency is a daunting task concerning the clinical diagnostic tools for patients. Hence, a …

Sex determination, gonadal sex differentiation, and plasticity in vertebrate species

Y Nagahama, T Chakraborty… - Physiological …, 2021 - journals.physiology.org
A diverse array of sex determination (SD) mechanisms, encompassing environmental to
genetic, have been found to exist among vertebrates, covering a spectrum from fixed SD …

Zebrafish: Housing and husbandry recommendations

P Aleström, L D'Angelo, PJ Midtlyng… - Laboratory …, 2020 - journals.sagepub.com
This article provides recommendations for the care of laboratory zebrafish (Danio rerio) as
part of the further implementation of Annex A to the European Convention on the protection …

The use of zebrafish (Danio rerio) as biomedical models

T Teame, Z Zhang, C Ran, H Zhang, Y Yang… - Animal …, 2019 - academic.oup.com
Implications Because of its fully sequenced genome, easy genetic manipulation, high
fecundity, external fertilization and rapid development, and nearly transparent embryo …

Zebrafish: development of a vertebrate model organism

JR Meyers - Current Protocols Essential Laboratory …, 2018 - Wiley Online Library
Zebrafish (Danio rerio) are a small‐bodied tropical, freshwater fish species originally from
South Asia. The ease of care, year‐round prolific breeding, and transparent, external …

Zebrafish models of cardiac disease: From fortuitous mutants to precision medicine

JM González-Rosa - Circulation research, 2022 - ahajournals.org
Heart disease is the leading cause of death worldwide. Despite decades of research, most
heart pathologies have limited treatments, and often the only curative approach is heart …

Zebrafish: a resourceful vertebrate model to investigate skeletal disorders

F Tonelli, JW Bek, R Besio, A De Clercq… - Frontiers in …, 2020 - frontiersin.org
Animal models are essential tools for addressing fundamental scientific questions about
skeletal diseases and for the development of new therapeutic approaches. Traditionally …

Zebrafish as a model for cardiovascular and metabolic disease: the future of precision medicine

RS Angom, NMR Nakka - Biomedicines, 2024 - mdpi.com
The zebrafish (Danio rerio) has emerged as an appreciated and versatile model organism
for studying cardiovascular and metabolic diseases, offering unique advantages for both …

Zebrafish heart failure models

S Narumanchi, H Wang, S Perttunen… - Frontiers in cell and …, 2021 - frontiersin.org
Heart failure causes significant morbidity and mortality worldwide. The understanding of
heart failure pathomechanisms and options for treatment remain incomplete. Zebrafish has …

Polystyrene microplastics enhance microcystin-LR-induced cardiovascular toxicity and oxidative stress in zebrafish embryos

Y **ao, L Hu, J Duan, H Che, W Wang, Y Yuan… - Environmental …, 2024 - Elsevier
The health risks associated with combined exposure to microplastics (MPs) and
cyanobacteria toxins have gained increasing attention due to the large-scale prevalence of …