The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …

The concentration of neurotransmitters in the extracellular space is tightly controlled by
distinct classes of membrane transport proteins. This review focuses on the molecular …

J. Neurochem.(2010) 10.1111/j. 1471‐4159.2010. 06599. x Abstract The dopamine
transporter (DAT) plays a key role in regulating dopaminergic signalling in the brain by …

Neurotransmitters, such as γ-aminobutyric acid, glutamate, acetyl choline, glycine and the
monoamines, facilitate the crosstalk within the central nervous system. The designated …

The catecholamine dopamine (DA) functions as a powerful modulatory neurotransmitter in
both invertebrates and vertebrates. As in man, DA neurons in the nematode Caenorhabditis …

The serotonin transporter (SERT) terminates neurotransmission by removing serotonin from
the synaptic cleft. In addition, it is the site of action of antidepressants (which block the …

As the first member of the solute carrier 6 (SLC6) protein family, the γ-aminobutyric acid
(GABA) transporter 1 (GAT1, SLC6A1), plays a pivotal role in the uptake of GABA from the …

Neurotransmitter transporters are critical for synaptic neurotransmitter inactivation.
Transporter inhibitors markedly increase the duration and magnitude of synaptic …

γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous
system (CNS). Its homeostasis is maintained by neuronal and glial GABA transporters …

Many membrane proteins incur a folding problem during biosynthesis; only a fraction thereof
is exported from the endoplasmic reticulum (ER), because quality control is stringent. This is …