Galectin-1 is a carbohydrate-binding protein expressed in many tissues. In recent years,
increasing evidence has emerged for the role of galectin-1 in obesity, insulin resistance and …

Autophagy, lipophagy, and mitophagy are considered to be the major recycling processes
for protein aggregates, excess fat, and damaged mitochondria in adipose tissues in …

A decline in β-cell function is a prerequisite for the development of type 2 diabetes, yet the
level of β-cell function in individuals at risk of the condition is rarely measured. This is due, in …

Improving nutrient utilization efficiency is essential for livestock, given the current scenario of
increasing demand for animal protein and sustainable resource use. In this context …

To treat obesity, suppression of white adipose tissue (WAT) expansion and activation of
brown adipose tissue (BAT) are considered as potential therapeutic targets. Recent …

Intramuscular fat (IMF) is an important trait for beef eating quality. The mechanism of how
IMF is deposited in beef cattle muscle is not clear at the molecular level. The muscle (M …

Objective To identify a potential therapeutic target for type 2 diabetes by comparing the
subcutaneous interstitial fluid from type 2 diabetes patients and healthy men. Methods …

As the largest energy storage reservoir, subcutaneous adipose tissue (SAT) stores excess
lipids by adipocytes enlargement and/or recruitment of new precursor cells. Energy overload …

Abstract Type-2 diabetes mellitus (T2DM) is an expanding global health problem, involving
defective insulin secretion by pancreatic β-cells and peripheral insulin resistance, leading to …

Galectin-1, a recently identified peptide, is primarily released from the adipose tissue.
Although galectin-1 was shown to have an anti-inflammatory effect, its specific function is not …