Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …

Long known as digestive organelles, lysosomes have now emerged as multifaceted centers
responsible for degradation, nutrient sensing, and immunity. Growing evidence also …

Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, but
an effective targeted therapy has not been well-established so far. Considering the lack of …

The extracellular matrix (ECM) is pivotal in modulating tumor progression. Besides
chemically stimulating tumor cells, it also offers physical support that orchestrates the …

Autologous therapies using adipose-derived stromal vascular fraction (AD-SVFs) and adult
adipose-derived mesenchymal stem cells (AD-MSCs) warrant careful preparation of the …

Obesity is a global pandemic and it is well evident that obesity is associated with the
development of many disorders including many cancer types. Breast cancer is one of that …

Triple-negative breast cancer (TNBC) cells are devoid of estrogen receptors (ERs),
progesterone receptor (PRs), and human epidermal growth factor receptor 2 (HER2), and it …

We have previously demonstrated that carnosol, a naturally occurring diterpene, inhibited in
vitro cell viability and colony growth, as well as induced cell cycle arrest, autophagy and …

The majority of breast cancer patients is treated with breast-conserving surgery (BCS)
combined with adjuvant radiation therapy. Up to 40% of patients has a tumor-positive …

Triple-negative breast cancer (TNBC) stands out as the most formidable variant of breast
cancer, predominantly affecting younger women and characterized by a bleak outlook and a …