TB being one of the deadliest diseases and second most common infectious cause of
deaths, poses the severe threat to global health. The extended duration of therapy owing to …

Growing resistance to antimicrobial medicines is a critical health problem that must be
urgently addressed. Adding to the increasing number of patients that succumb to infections …

Resistance to amikacin and other major aminoglycosides is commonly due to enzymatic
acetylation by the aminoglycoside 6′-N-acetyltransferase type I enzyme, of which type Ib …

As a continuation of our efforts to develop new agrochemicals with typical architecture and
efficient bioactivity from plant natural products, natural neolignan honokiol was used as a …

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb),
which remains a significant global health challenge. The emergence of multidrug-resistant …

Acute lung injury (ALI) is an inflammation-mediated respiratory disease that is associated
with a high mortality rate. In this study, a series of novel O-benzylcinnamic acid derivatives …

Over one and a half million people die of tuberculosis (TB) each year. Multidrug-resistant TB
infections are especially dangerous, and new drugs are needed to combat them. The high …

Introduction Protein acetylation is an extensively investigated post-translational modification
(PTM). In addition to lysine acetylation, three new types of lysine acylations characterized by …

Aminoglycosides are bactericidal antibiotics with a broad spectrum of activity, used to treat
infections caused mostly by Gram-negative pathogens and as a second-line therapy against …

Abstract Pt (II) and Pd (II) coordinating N‐donor ligands have been extensively studied as
anticancer agents after the success of cisplatin. In this work, a novel bidentate N‐donor …