Idiopathic pulmonary fibrosis: Disease mechanisms and drug development
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease of unknown cause
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life …
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life …
Idiopathic pulmonary fibrosis: an update on pathogenesis
Q Mei, Z Liu, H Zuo, Z Yang, J Qu - Frontiers in pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal fibrotic lung disease that occurs
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …
[HTML][HTML] Targeting PI3K/AKT signaling for treatment of idiopathic pulmonary fibrosis
J Wang, K Hu, X Cai, B Yang, Q He, J Wang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic interstitial pneumonia
with unknown causes. The incidence rate increases year by year and the prognosis is poor …
with unknown causes. The incidence rate increases year by year and the prognosis is poor …
Senescence of alveolar type 2 cells drives progressive pulmonary fibrosis
Rationale: Idiopathic pulmonary fibrosis (IPF) is an insidious and fatal interstitial lung
disease associated with declining pulmonary function. Accelerated aging, loss of epithelial …
disease associated with declining pulmonary function. Accelerated aging, loss of epithelial …
[HTML][HTML] From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic?
While the coronavirus disease 19 (COVID-19) pandemic has transformed the medical and
scientific communites since it was first reported in late 2019, we are only beginning to …
scientific communites since it was first reported in late 2019, we are only beginning to …
The leading role of epithelial cells in the pathogenesis of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive and devastating interstitial
lung disease of unknown etiology, where the normal lung architecture is lost and replaced …
lung disease of unknown etiology, where the normal lung architecture is lost and replaced …
Genome-wide association study of susceptibility to idiopathic pulmonary fibrosis
Rationale: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease characterized by
scarring of the lung that is believed to result from an atypical response to injury of the …
scarring of the lung that is believed to result from an atypical response to injury of the …
Hypersensitivity pneumonitis
Hypersensitivity pneumonitis (HP) is a complex syndrome caused by the inhalation of a
variety of antigens in susceptible and sensitized individuals. These antigens are found in the …
variety of antigens in susceptible and sensitized individuals. These antigens are found in the …
Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia
Disclosures: C. Flores reported grants from Instituto de Salud Carlos III, Spanish Ministry of
Science and Innovation, and Cabildo Insular de Tenerife outside the submitted work. J …
Science and Innovation, and Cabildo Insular de Tenerife outside the submitted work. J …
[HTML][HTML] Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease of unknown etiology. It is
characterized by deposition of extracellular matrix proteins, like collagen and fibronectin in …
characterized by deposition of extracellular matrix proteins, like collagen and fibronectin in …