Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022‏ - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Rest and exercise early after sport-related concussion: a systematic review and meta-analysis

JJ Leddy, JS Burma, CM Toomey, A Hayden… - British journal of sports …, 2023‏ - bjsm.bmj.com
Objective To synthesise the evidence regarding the risks and benefits of physical activity
(PA), prescribed aerobic exercise treatment, rest, cognitive activity and sleep during the first …

Clinical recovery from concussion–return to school and sport: a systematic review and meta-analysis

M Putukian, L Purcell, KJ Schneider… - British journal of sports …, 2023‏ - bjsm.bmj.com
Objective To define the time frames, measures used and modifying factors influencing
recovery, return to school/learn (RTL) and return to sport (RTS) after sport-related …

Sex differences in traumatic brain injury: what we know and what we should know

RP Gupte, WM Brooks, RR Vukas, JD Pierce… - Journal of …, 2019‏ - liebertpub.com
There is growing recognition of the problem of male bias in neuroscience research,
including in the field of traumatic brain injury (TBI) where fewer women than men are …

Centers for Disease Control and Prevention guideline on the diagnosis and management of mild traumatic brain injury among children

A Lumba-Brown, KO Yeates, K Sarmiento… - JAMA …, 2018‏ - jamanetwork.com
Importance Mild traumatic brain injury (mTBI), or concussion, in children is a rapidly growing
public health concern because epidemiologic data indicate a marked increase in the …

Early subthreshold aerobic exercise for sport-related concussion: a randomized clinical trial

JJ Leddy, MN Haider, MJ Ellis, R Mannix… - JAMA …, 2019‏ - jamanetwork.com
Importance Sport-related concussion (SRC) is a significant public health problem without an
effective treatment. Objective To assess the effectiveness of subsymptom threshold aerobic …

Prevention strategies and modifiable risk factors for sport-related concussions and head impacts: a systematic review and meta-analysis

PH Eliason, JM Galarneau, AT Kolstad… - British journal of sports …, 2023‏ - bjsm.bmj.com
Objectives To evaluate prevention strategies, their unintended consequences and
modifiable risk factors for sport-related concussion (SRC) and/or head impact risk. Design …

Early targeted heart rate aerobic exercise versus placebo stretching for sport-related concussion in adolescents: a randomised controlled trial

JJ Leddy, CL Master, R Mannix, DJ Wiebe… - The Lancet Child & …, 2021‏ - thelancet.com
Background Sport-related concussion is a public health problem, particularly in adolescents.
Quality of life is reduced in adolescents with persistent post-concussive symptoms …

A multidimensional approach to post-concussion symptoms in mild traumatic brain injury

S Polinder, MC Cnossen, RGL Real, A Covic… - Frontiers in …, 2018‏ - frontiersin.org
Mild traumatic brain injury (mTBI) presents a substantial burden to patients, families, and
health care systems. Whereas, recovery can be expected in the majority of patients, a subset …

The natural history of sport-related concussion in collegiate athletes: findings from the NCAA-DoD CARE Consortium

SP Broglio, T McAllister, BP Katz, M LaPradd, W Zhou… - Sports medicine, 2022‏ - Springer
Background Sport-related concussion is recognized as a significant injury with variable
recovery rates. Objective This study defined the acute natural history of sport concussion in …