The activation of stress-related neuroendocrine systems helps to maintain homeostasis, but
excessive stress can damage body functions. We review current evidence from basic …

Objective This meta-review aimed to present all available quantitative pooled estimates for
the associations between psychosocial work exposures and health outcomes using a …

Cardiovascular disease remains the leading cause of disease burden globally, which
underlies the continuing need to identify new complementary targets for prevention. Over the …

Importance It is well established that selected lifestyle factors are individually associated
with lower risk of chronic diseases, but how combinations of these factors are associated …

Background Long working hours might increase the risk of cardiovascular disease, but
prospective evidence is scarce, imprecise, and mostly limited to coronary heart disease. We …

Background: Epidemiologic evidence for work stress as a risk factor for coronary heart
disease is mostly based on a single measure of stressful work known as job strain, a …

Background Although there is substantial evidence of differential hypothalamic-pituitary-
adrenal (HPA) axis activity in both generalized and abdominal obesity, consistent trends in …

The physiological reaction to psychological stress, involving the hypothalamic–pituitary–
adrenocortical and sympatho–adrenomedullary axes, is well characterized, but its link to …

Background Published work assessing psychosocial stress (job strain) as a risk factor for
coronary heart disease is inconsistent and subject to publication bias and reverse causation …

Considerable progress has been made during the past decade in research on
cardiovascular effects of stress. Early-life stressors, such as childhood abuse and early …