Recent far-reaching advances in synthetic biology have yielded exciting tools for the
creation of new materials. Conversely, advances in the fundamental understanding of soft …

Reproducibility of scientific results is a key element of science and credibility. The lack of
reproducibility across many scientific fields has emerged as an important concern. In this …

Digital twins represent a key technology for precision health. Medical digital twins consist of
computational models that represent the health state of individual patients over time …

Simulation experiments are typically conducted repeatedly during the model development
process, for example, to revalidate if a behavioral property still holds after several model …

The “COmputational Modeling in BIology NEtwork”(COMBINE) initiative aims to harmonise
the development of diverse community standards for computational models in biology [1, 2] …

Abstract The Systems Biology community has taken numerous actions to develop data and
modeling standards towards FAIR data and model handling. Nevertheless, the debate about …

This special issue of the Journal of Integrative Bioinformatics contains updated
specifications of COMBINE standards in systems and synthetic biology. The 2022 special …

Specifications of standards in systems and synthetic biology: status and developments in 2020
Skip to content Should you have institutional access? Here's how to get it ... De Gruyter € EUR …

Interest in the concept of a virtual human model that can encompass human physiology and
anatomy on a biophysical (mechanistic) basis, and can assist with the clinical diagnosis and …

In this white paper, we describe the founding of a new ELIXIR Community-the Systems
Biology Community-and its proposed future contributions to both ELIXIR and the broader …