Recent far-reaching advances in synthetic biology have yielded exciting tools for the
creation of new materials. Conversely, advances in the fundamental understanding of soft …

Microbiomes, comprised of diverse microbial species and viruses, play pivotal roles in
human health, environmental processes, and biotechnological applications and interact with …

Reproducibility of scientific results is a key element of science and credibility. The lack of
reproducibility across many scientific fields has emerged as an important concern. In this …

Digital twins represent a key technology for precision health. Medical digital twins consist of
computational models that represent the health state of individual patients over time …

Simulation experiments are typically conducted repeatedly during the model development
process, for example, to revalidate if a behavioral property still holds after several model …

Abstract The Systems Biology community has taken numerous actions to develop data and
modeling standards towards FAIR data and model handling. Nevertheless, the debate about …

The “COmputational Modeling in BIology NEtwork”(COMBINE) initiative aims to harmonise
the development of diverse community standards for computational models in biology [1, 2] …

Abstract Background The Biology System Description Language (BiSDL) is an accessible,
easy-to-use computational language for multicellular synthetic biology. It allows synthetic …

Specifications of standards in systems and synthetic biology: status and developments in 2020
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This special issue of the Journal of Integrative Bioinformatics contains updated
specifications of COMBINE standards in systems and synthetic biology. The 2022 special …