Green chemistry in the synthesis of pharmaceuticals

S Kar, H Sanderson, K Roy, E Benfenati… - Chemical …, 2021 - ACS Publications
The principles of green chemistry (GC) can be comprehensively implemented in green
synthesis of pharmaceuticals by choosing no solvents or green solvents (preferably water) …

Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

Review on the Ugi multicomponent reaction mechanism and the use of fluorescent derivatives as functional chromophores

RO Rocha, MO Rodrigues, BAD Neto - ACS omega, 2020 - ACS Publications
In the present mini-review we discuss the findings, controversies, and gaps observed for the
Ugi four-component reaction. The Ugi multicomponent reaction, performed by mixing an …

Catalytic approaches to multicomponent reactions: A critical review and perspectives on the roles of catalysis

BAD Neto, RO Rocha, MO Rodrigues - Molecules, 2021 - mdpi.com
In this review, we comprehensively describe catalyzed multicomponent reactions (MCRs)
and the multiple roles of catalysis combined with key parameters to perform these …

Cobalt (III)-catalyzed diastereo-and enantioselective three-component C–H functionalization

AG Herraiz, N Cramer - Acs Catalysis, 2021 - ACS Publications
Catalytic enantioselective C–H functionalization has recently become a tool for the creation
of stereogenic centers. The steep increase in molecular complexity of multicomponent …

Recent advances in catalytic enantioselective multicomponent reactions

PSG Nunes, HDA Vidal, AG Corrêa - Organic & Biomolecular …, 2020 - pubs.rsc.org
Multicomponent reactions (MCRs) undoubtedly correspond to one of the synthetic strategies
that best fit the new demands of chemistry for presenting high atom economy and enabling …

Gold-catalyzed multicomponent reactions

AG Tathe, SS Saswade, NT Patil - Organic Chemistry Frontiers, 2023 - pubs.rsc.org
Multicomponent reactions (MCRs) have emerged as an important branch in organic
synthesis for the creation of complex molecular structures from more than two starting …

Facile route to synthesize Fe 3 O 4@ acacia–SO 3 H nanocomposite as a heterogeneous magnetic system for catalytic applications

R Taheri-Ledari, MS Esmaeili, Z Varzi… - RSC …, 2020 - pubs.rsc.org
In this work, a novel catalytic system for facilitating the organic multicomponent synthesis of
9-phenyl hexahydroacridine pharmaceutical derivatives is reported. Concisely, this catalyst …

Access to N−CF3 Formamides by Reduction of N−CF3 Carbamoyl Fluorides

FG Zivkovic, C D.‐T. Nielsen… - Angewandte …, 2022 - Wiley Online Library
The departure into unknown chemical space is essential for the discovery of new properties
and function. We herein report the first synthetic access to N‐trifluoromethylated formamides …

A comprehensive survey upon diverse and prolific applications of chitosan-based catalytic systems in one-pot multi-component synthesis of heterocyclic rings

H Mousavi - International Journal of Biological Macromolecules, 2021 - Elsevier
Heterocyclic compounds are among the most prestigious and valuable chemical molecules
with diverse and magnificent applications in various sciences. Due to the remarkable and …