[HTML][HTML] Bioactivity and development of small non-platinum metal-based chemotherapeutics

MG Ferraro, M Piccolo, G Misso, R Santamaria, C Irace - Pharmaceutics, 2022 - mdpi.com
Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …

Multifunctional nanoparticle for cancer therapy

Y Gao, K Wang, J Zhang, X Duan, Q Sun, K Men - MedComm, 2023 - Wiley Online Library
Cancer is a complex disease associated with a combination of abnormal physiological
process and exhibiting dysfunctions in multiple systems. To provide effective treatment and …

Develo** a multitargeted anticancer palladium (II) agent based on the His-242 residue in the IIA subdomain of human serum albumin

W Li, S Li, Z Zhang, G Xu, X Man, F Yang… - Journal of Medicinal …, 2023 - ACS Publications
To obtain next-generation metal drugs that can overcome the deficiencies of platinum (Pt)
drugs and treat cancer more effectively, we proposed to develop a multitargeted palladium …

Biosynthesis of palladium, platinum, and their bimetallic nanoparticles using rosemary and ginseng herbal plants: Evaluation of anticancer activity

M Alinaghi, P Mokarram, M Ahmadi… - Scientific Reports, 2024 - nature.com
In this research, palladium (II) and platinum (II), as well as their bimetallic nanoparticles were
synthesized using medicinal plants in an eco-friendly manner. Rosemary and Ginseng …

[HTML][HTML] The importance of being Casiopeina as polypharmacologycal profile (mixed chelate–copper (II) complexes and their in vitro and in vivo activities)

Z Aguilar-Jiménez, A Espinoza-Guillén… - Inorganics, 2023 - mdpi.com
In this review, we present a timeline that shows the origin of mixed chelate copper (II)
complexes, registered as Mark Title Casiopeínas®, as the first copper (II) compounds …

Develo** a palladium (II) agent to overcome multidrug resistance and metastasis of liver tumor by targeted multiacting on tumor cell, inactivating cancer-associated …

M Jiang, W Li, J Liang, M Pang, S Li, G Xu… - Journal of Medicinal …, 2024 - ACS Publications
To targeted overcome the multidrug resistance (MDR) and metastasis of liver tumors, we
proposed to develop a palladium (Pd) agent based on a specific residue of human serum …

Spectroscopic inspection, DFT analysis, biological evaluation and molecular docking studies of new 2-(phenylamino) acetohydrazide hydrazone based-transition …

TI Kashar, SS Hassan, HA El-Boraey - Inorganica Chimica Acta, 2024 - Elsevier
The binuclear Pd (II) and mononuclear Zn (II), Ru (III) and Pt (IV) chelates were synthesized
based on new hydrazone ligand derived from 2-(phenylamino) acetohydrazide and 3-Acetyl …

Discovery of the Next-Generation Platinum-Based Anticancer Agents for Combating Oxaliplatin-Induced Drug Resistance

Z Sun, J Han, J Xu, W Song, Y Cui, Y Liu… - Journal of Medicinal …, 2024 - ACS Publications
Oxaliplatin-based chemotherapy has proven to be one of the most effective treatments for
advanced or metastatic colorectal cancer. However, increasing clinical resistance to …

[HTML][HTML] Metal complexes of saccharin and thiosaccharin as potential anticancer and antimicrobial agents

C Icsel, VT Yilmaz, OZ Yesilel, WTA Harrison - European Journal of …, 2024 - Elsevier
Based on the chemotherapeutic success of cisplatin, carboplatin and oxaliplatin as
anticancer drugs, and silver sulfadiazine (AgSDZ) as an antibacterial drug, exploration of the …

Electrospun silk fibroin and collagen composite nanofiber incorporated with palladium and platinum nanoparticles for wound dressing applications

M Arumugam, B Murugesan, D Chinnalagu… - Journal of Polymers and …, 2024 - Springer
In the field of biomedical engineering, nanofiber scaffolds have excellent biomaterial
properties, making them highly suitable for superior wound dressing applications. This work …