[HTML][HTML] Is melatonin the cornucopia of the 21st century?

N Ferlazzo, G Andolina, A Cannata, MG Costanzo… - Antioxidants, 2020 - mdpi.com
Melatonin, an indoleamine hormone produced and secreted at night by pinealocytes and
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …

Melatonin membrane receptors in peripheral tissues: distribution and functions

RM Slominski, RJ Reiter… - Molecular and cellular …, 2012 - Elsevier
Many of melatonin's actions are mediated through interaction with the G-protein coupled
membrane bound melatonin receptors type 1 and type 2 (MT1 and MT2, respectively) or …

The crosstalk between melatonin and sex steroid hormones

J Cipolla-Neto, FG Amaral, JM Soares Jr… - …, 2022 - karger.com
Melatonin, an indolamine mainly released from the pineal gland, is associated with many
biological functions, namely, the modulation of circadian and seasonal rhythms, sleep …

Adverse events associated with oral administration of melatonin: A critical systematic review of clinical evidence

HM Foley, AE Steel - Complementary therapies in medicine, 2019 - Elsevier
While melatonin was once thought of simply as a sleep-inducing hormone, recent research
has resulted in development of a deeper understanding of the complex physiological activity …

Curcumin and endometriosis

A Vallée, Y Lecarpentier - International journal of molecular sciences, 2020 - mdpi.com
Endometriosis is one of the main common gynecological disorders, which is characterized
by the presence of glands and stroma outside the uterine cavity. Some findings have …

The role of sex hormones and steroid receptors on female reproductive cancers

LG de Almeida Chuffa, LA Lupi-Júnior, AB Costa… - Steroids, 2017 - Elsevier
Sex steroids have been widely described to be associated with a number of human
diseases, including hormone-dependent tumors. Several studies have been concerned …

Melatonin promotes uterine and placental health: potential molecular mechanisms

LG de Almeida Chuffa, LA Lupi, MS Cucielo… - International journal of …, 2019 - mdpi.com
The development of the endometrium is a cyclic event tightly regulated by hormones and
growth factors to coordinate the menstrual cycle while promoting a suitable …

Efficacy of melatonin in the treatment of endometriosis: a phase II, randomized, double-blind, placebo-controlled trial

A Schwertner, CCC Dos Santos, GD Costa, A Deitos… - PAIN®, 2013 - Elsevier
Endometriosis-associated chronic pelvic pain (EACPP) presents with an intense
inflammatory reaction. Melatonin has emerged as an important analgesic, antioxidant, and …

Mechanisms of probiotic modulation of ovarian sex hormone production and metabolism: a review

X Liu, X Chen, C Wang, J Song, J Xu, Z Gao… - Food & Function, 2024 - pubs.rsc.org
Sex hormones play a pivotal role in the growth and development of the skeletal,
neurological, and reproductive systems. In women, the dysregulation of sex hormones can …

From implantation to birth: insight into molecular melatonin functions

G Carlomagno, M Minini, M Tilotta, V Unfer - International journal of …, 2018 - mdpi.com
Melatonin is a lipophilic hormone synthesized and secreted mainly in the pineal gland,
acting as a neuroendocrine transducer of photoperiodic information during the night. In …