Viral infections can give rise to a systemic decrease in the total number of lymphocytes in the
blood, referred to as lymphopenia. Lymphopenia may affect the host adaptive immune …

Innate immunity is the first line of the host immune system to fight against infections. Natural
killer cells are the innate immunity lymphocytes responsible for fighting against virus …

Ebola virus (EBOV) disease (EVD) results from an exacerbated immunological response
that is highlighted by a burst in the production of inflammatory mediators known as a …

Specific host pathways that may be targeted therapeutically to inhibit the replication of Ebola
virus (EBOV) and other emerging viruses remain incompletely defined. A screen of 200,000 …

Some monoclonal antibodies (mAbs) recovered from survivors of filovirus infections can
protect against infection. It is currently unknown whether natural infection also induces some …

Ebola virus (EBOV), a member of the Filoviridae family, is a highly pathogenic virus that
causes severe hemorrhagic fever in humans and is responsible for epidemics throughout …

ABSTRACT Marburg (MARV) and Ebola (EBOV) viruses are zoonotic pathogens that cause
severe hemorrhagic fever in humans. The natural reservoir of MARV is the Egyptian rousette …

Fatal outcomes of Ebola virus (EBOV) infections are typically preceded by a 'sepsis-
like'syndrome and lymphopenia despite T cells being resistant to Ebola infection. The …

Ebola virus (EBOV), belonging to the species Zaire ebolavirus in the genus Ebolavirus,
causes a severe febrile illness in humans with case fatality rates (CFRs) up to 90%. While …

Viruses as obligate intracellular parasites require their host to replicate them and to facilitate
their spread to others. In humans, viral infections are rarely lethal, even if they are highly …