Introduction: Molecular dynamics (MD) simulations can provide not only plentiful dynamical
structural information on biomacromolecules but also a wealth of energetic information …

Significance: This review highlights the critical role of transforming growth factor beta (TGF-
β) 1–3 within different phases of wound healing, in particular, late-stage wound healing. It is …

Objective: To update the 1994 practice parameter for the diagnosis of dementia in the
elderly. Background: The AAN previously published a practice parameter on dementia in …

The development of technologies for the in vitro amplification of abnormal conformations of
prion protein (PrPSc) has generated the potential for sensitive detection of prions. Here we …

The 14-3-3 proteins are a family of conserved regulatory molecules expressed in all
eukaryotic cells. A striking feature of the 14-3-3 proteins is their ability to bind a multitude of …

Cerebrospinal fluid (CSF) is a clear, transparent fluid derived from blood plasma that
protects the brain and spinal cord against mechanical shock, provides buoyancy, clears …

Bovine spongiform encephalopathy (BSE) and human Creutzfeldt-Jakob disease (CJD) are
among the most notable central nervous system degenerative disorders caused by prions …

The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

3-3 proteins are abundantly expressed in the brain and have been detected in the
cerebrospinal fluid of patients with different neurological disorders. Although the function of …

One of the most strikingrags to riches' stories in the protein world is that of 14-3-3, originally
identified in 1967 as merely an abundant brain protein. The first clues that 14-3-3 would play …