Trefoil factor (TFF) peptides, with a 40-amino acid motif and including six conserved cysteine
residues that form intramolecular disulfide bonds, are a family of mucin-associated secretory …

Current treatments for diabetic ulcers (DUs) remain unsatisfactory due to the risk of bacterial
infection and impaired angiogenesis during the healing process. The increased degradation …

Chronic liver disease is a major public health problem with a high and increasing
prevalence worldwide. In the progression of chronic liver disease, steatosis drives the …

Chronic diabetic wounds are a severe complication of diabetes, often leading to high
treatment costs and high amputation rates. Numerous studies have revealed that nitric oxide …

Macrophages, which exhibit great plasticity, are important components of the inflamed tissue
and constitute an essential element of regenerative responses. Epithelial Wnt signalling is …

A defective induction of epithelial autophagy may have a role in the pathogenesis of
inflammatory bowel diseases. This process is regulated mainly by extracellular factors such …

Myopia is one of the most common eye diseases in children and adolescents worldwide.
Currently, there is no effective treatment in clinical practice. Ocular tissue fibrosis is involved …

Background Curcuma purpurascens BI. is a medicinal plant from the Zingiberaceae family,
which is widely used as a spice and as folk medicine. The aim of the present study is to …

Abstract Background: The Notch signalling pathway plays an essential role in mucosal
regeneration, which constitutes a key goal of Crohn's disease (CD) treatment. Macrophages …

Preeclampsia is a pregnancy-specific syndrome, defined by such clinical hallmarks as the
onset of maternal hypertension and proteinuria after 20 weeks of gestation. The syndrome is …