Microbiota medicine: towards clinical revolution
The human gastrointestinal tract is inhabited by the largest microbial community within the
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …
Hyaluronan: molecular size‐dependent signaling and biological functions in inflammation and cancer
AG Tavianatou, I Caon, M Franchi… - The FEBS …, 2019 - Wiley Online Library
Hyaluronan (HA) is a linear nonsulfated glycosaminoglycan of the extracellular matrix that
plays a pivotal role in a variety of biological processes. High‐molecular weight HA exhibits …
plays a pivotal role in a variety of biological processes. High‐molecular weight HA exhibits …
Proteoglycan chemical diversity drives multifunctional cell regulation and therapeutics
The extracellular matrix (ECM) constitutes a highly dynamic three-dimensional structural
network comprised of macromolecules, such as proteoglycans/glycosaminoglycans …
network comprised of macromolecules, such as proteoglycans/glycosaminoglycans …
Glutamatergic signaling along the microbiota-gut-brain axis
A complex bidirectional communication system exists between the gastrointestinal tract and
the brain. Initially termed the “gut-brain axis” it is now renamed the “microbiota-gut-brain …
the brain. Initially termed the “gut-brain axis” it is now renamed the “microbiota-gut-brain …
Tryptophan metabolites along the microbiota-gut-brain axis: an interkingdom communication system influencing the gut in health and disease
A Bosi, D Banfi, M Bistoletti… - International Journal of …, 2020 - journals.sagepub.com
The 'microbiota-gut-brain axis' plays a fundamental role in maintaining host homeostasis,
and different immune, hormonal, and neuronal signals participate to this interkingdom …
and different immune, hormonal, and neuronal signals participate to this interkingdom …
Revisiting the hallmarks of cancer: The role of hyaluronan
I Caon, B Bartolini, A Parnigoni, E Caravà… - Seminars in cancer …, 2020 - Elsevier
Extracellular matrix (ECM) is a complex network of macromolecules such as proteoglycans
(PGs), glycosaminoglycans (GAGs) and fibrous proteins present within all tissues and …
(PGs), glycosaminoglycans (GAGs) and fibrous proteins present within all tissues and …
Inflammation, extracellular matrix remodeling, and proteostasis in tumor microenvironment
M Marozzi, A Parnigoni, A Negri, M Viola… - International journal of …, 2021 - mdpi.com
Cancer is a multifaceted and complex pathology characterized by uncontrolled cell
proliferation and decreased apoptosis. Most cancers are recognized by an inflammatory …
proliferation and decreased apoptosis. Most cancers are recognized by an inflammatory …
Impact of microbial metabolites on microbiota–gut–brain axis in inflammatory bowel disease
The complex bidirectional communication system existing between the gastrointestinal tract
and the brain initially termed the “gut–brain axis” and renamed the “microbiota–gut–brain …
and the brain initially termed the “gut–brain axis” and renamed the “microbiota–gut–brain …
The complex interplay between extracellular matrix and cells in tissues
D Manou, I Caon, P Bouris, IE Triantaphyllidou… - The extracellular matrix …, 2019 - Springer
Extracellular matrix (ECM) maintains the structural integrity of tissues and regulates cell and
tissue functions. ECM is comprised of fibrillar proteins, proteoglycans (PGs) …
tissue functions. ECM is comprised of fibrillar proteins, proteoglycans (PGs) …
Cell energy metabolism and hyaluronan synthesis
I Caon, A Parnigoni, M Viola… - … of Histochemistry & …, 2021 - journals.sagepub.com
Hyaluronan (HA) is a linear glycosaminoglycan (GAG) of extracellular matrix (ECM)
synthesized by three hyaluronan synthases (HASes) at the plasma membrane using uridine …
synthesized by three hyaluronan synthases (HASes) at the plasma membrane using uridine …