Continuous proliferation of tumor cells requires constant adaptations of energy metabolism
to rapidly fuel cell growth and division. This energetic adaptation often comprises …

Oxidative stress and AKT serine-threonine kinase (AKT) are responsible for regulating
several cell functions of cancer cells. Several natural products modulate both oxidative …

As a substrate and major effector of the mammalian target of rapamycin complex 1
(mTORC1), the biological functions of ribosomal protein S6 kinase (S6K) have been …

Covering: up to the end of 2022 Microorganisms are exceptional sources of a wide array of
unique natural products and play a significant role in drug discovery. During the golden era …

Breast cancer stands as the most prevalent cancer in women globally, and contributes to the
highest percentage of mortality due to cancer-related deaths in women. Paclitaxel (PTX) is …

Bacteria are rich in a wide variety of secondary metabolites, such as pigments, alkaloids,
antibiotics, and others. These bioactive microbial products serve a great application in …

Cervical cancer is the fourth most common cancer among women worldwide. Though
several natural products have been reported regarding their efficacies against cervical …

As the leading cause of cancer death, cervical cancer ranks fourth for both incidence and
mortality. Cervical cancer incidence and mortality rates have reportedly decreased over the …

The Actinomycetia isolate, MNP32 was isolated from the Manas National Park of Assam,
India, located in the Indo-Burma biodiversity hotspot region of Northeast India …

Background Oral squamous cell carcinoma (OSCC) is the most prevalent malignancy in the
world with an alarming rate of mortality. Despite the advancement in treatment strategies …