Objective: Cognitive remediation therapy for schizophrenia was developed to treat cognitive
problems that affect functioning, but the treatment effects may depend on the type of trial …

This paper will review a series of studies using the Experience Sampling Method that
suggest that altered sensitivity to stress is an endophenotype for psychosis. The Experience …

Background Proponents of early intervention have argued that outcomes might be improved
if more therapeutic efforts were focused on the early stages of schizophrenia or on people …

Background The quality of the therapeutic alliance (TA) has been invoked to explain the
equal effectiveness of different psychotherapies, but prior research is correlational, and does …

Voice hearing (VH) is often regarded as pathognomic for schizophrenia. The purpose of this
article is to review and integrate historical, clinical, epidemiological, and phenomenological …

Cognitive behavior therapy (CBT) has been demonstrated in a number of randomized
controlled trials to be efficacious as an adjunctive treatment for psychotic disorders …

BackgroundNegative symptoms observed in patients with psychotic disorders undermine
quality of life and functioning. Antipsychotic medications have a limited impact …

How does an excess in a neurochemical lead someone to being paranoid about the
intentions of their neighbour? And why does blocking a dopamine receptor improve this …

Complex intervention trials should be able to answer both pragmatic and explanatory
questions in order to test the theories motivating the intervention and help understand the …

These updated guidelines from the British Association for Psychopharmacology replace the
original version published in 2011. They address the scope and targets of pharmacological …