[HTML][HTML] Jet injectors: Perspectives for small volume delivery with lasers

J Schoppink, DF Rivas - Advanced drug delivery reviews, 2022 - Elsevier
Needle-free jet injectors have been proposed as an alternative to injections with hypodermic
needles. Currently, a handful of commercial needle-free jet injectors already exist. However …

Towards more tolerable subcutaneous administration: Review of contributing factors for improving combination product design

N Mathias, S Huille, M Picci, RP Mahoney… - Advanced Drug Delivery …, 2024 - Elsevier
Subcutaneous (SC) injections can be associated with local pain and discomfort that is
subjective and may affect treatment adherence and overall patient experience. With …

The effect of jet speed on large volume jet injection

JW McKeage, BP Ruddy, PMF Nielsen… - Journal of Controlled …, 2018 - Elsevier
Jet injection presents a promising alternative to needle and syringe injection for transdermal
drug delivery. The controllability of recently-developed jet injection devices now allows jet …

Optimization of portable electronically controlled needle-free jet injection systems

BP Ruddy, AW Dixon, RMJ Williams… - IEEE/ASME …, 2017 - ieeexplore.ieee.org
Jet injection is a process by which a fluid drug is delivered through the skin in the form of a
high-velocity jet. Powering jet injection using a controllable actuator, such as a moving-coil …

Power-efficient controlled jet injection using a compound ampoule

JW McKeage, BP Ruddy, PMF Nielsen… - Journal of controlled …, 2018 - Elsevier
We present a new mechanism for achieving needle free jet injection that significantly
reduces the power required to perform a given injection. Our 'compound ampoule'produces …

Experimental investigation on penetration performance of larger volume needle-free injection device

D Zeng, N Wu, L Qian, H Shi, Y Kang - Journal of Mechanical Science and …, 2020 - Springer
The injection performance of a small volume of needle-free injection (up to 0.3 mL) has
proven to be controllable and satisfactory in transdermal drug delivery. However, no …

A linear permanent magnet synchronous motor for large volume needle-free jet injection

NNL Do, AJ Taberner, BP Ruddy - IEEE Transactions on …, 2018 - ieeexplore.ieee.org
Needle-free jet injection allows delivery of liquid drugs through the skin in the form of a
narrow fluid jet traveling at high speed, minimizing the risk of accidents. The use of a …

A novel controllable pneumatic needle-free injection system for larger-volume drug delivery

D Zeng, N Wu, L Qian, H Shi, Y Kang - Journal of Pharmaceutical Sciences, 2020 - Elsevier
Hypodermic needles and syringes are currently the main route of the transdermal
administration. Many complaints associated with needle-stick injuries, needle phobia, and …

Experimental investigation of the optimal driving pressure for a larger-volume controllable jet injection system

D Zeng, Z Tang, W Wang, Z Wang, J Li - Medical Engineering & Physics, 2023 - Elsevier
Jet injection technology has become the alternative drug delivery method of conventional
needle-based injection due to its obvious advantages. In order to meet the demand for …

Design of a linear permanent magnet synchronous motor for needle-free jet injection

NNL Do, AJ Taberner, BP Ruddy - 2017 IEEE Energy …, 2017 - ieeexplore.ieee.org
Needle-free jet injection allows delivery of liquid drugs through the skin in the form of a
narrow fluid jet traveling at high speed, minimizing the risk of accidents. The use of a …