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Amyloid-β: a potential link between epilepsy and cognitive decline
People with epilepsy—in particular, late-onset epilepsy of unknown aetiology—have an
elevated risk of dementia, and seizures have been detected in the early stages of Alzheimer …
elevated risk of dementia, and seizures have been detected in the early stages of Alzheimer …
[HTML][HTML] GABAergic dysfunction, neural network hyperactivity and memory impairments in human aging and Alzheimer's disease
J Jiménez-Balado, TS Eich - Seminars in cell & developmental biology, 2021 - Elsevier
In this review, we focus on the potential role of the γ-aminobutyric acidergic (GABAergic)
system in age-related episodic memory impairments in humans, with a particular focus on …
system in age-related episodic memory impairments in humans, with a particular focus on …
Clinical, imaging, and biomarker evidence of amyloid-and tau-related neurodegeneration in late-onset epilepsy of unknown etiology
LB Hickman, JM Stern, DHS Silverman… - Frontiers in …, 2023 - frontiersin.org
Accumulating evidence suggests amyloid and tau-related neurodegeneration may play a
role in development of late-onset epilepsy of unknown etiology (LOEU). In this article, we …
role in development of late-onset epilepsy of unknown etiology (LOEU). In this article, we …
Post-stroke everything
A Lekoubou, C Nguyen, M Kwon, AD Nyalundja… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review This review aims at providing updates on selected post-stroke
complications. We examined recent advances in diagnosing and treating the following post …
complications. We examined recent advances in diagnosing and treating the following post …
Epileptogenicity of white matter lesions in cerebral small vessel disease: a systematic review and meta-analysis
JI Doerrfuss, JM Hebel, M Holtkamp - Journal of neurology, 2023 - Springer
Background The epileptogenic properties of white matter lesions (WML) in cerebral small
vessel disease (CSVD) are not yet understood. The aim of our systematic review and meta …
vessel disease (CSVD) are not yet understood. The aim of our systematic review and meta …
[HTML][HTML] Late-onset epilepsy clinic: from clinical diagnostics to biomarkers
V Punia, S Bhansali, C Tsai - Seizure: European Journal of Epilepsy, 2024 - Elsevier
The unique patho-clinical entity of late-onset epilepsy (LOE), distinguished by its distinct
natural history, from its onset to the prognosis it portends, necessitates specialized care. We …
natural history, from its onset to the prognosis it portends, necessitates specialized care. We …
Mortality in patients with late-onset epilepsy: results from the atherosclerosis risk in communities study
Background and Objectives To determine the risk of mortality and causes of death in
persons with late-onset epilepsy (LOE) compared to those without epilepsy in a community …
persons with late-onset epilepsy (LOE) compared to those without epilepsy in a community …
Association between structural brain MRI abnormalities and epilepsy in older adults
Objective To determine the association between brain MRI abnormalities and incident
epilepsy in older adults. Methods Men and women (ages 45–64 years) from the …
epilepsy in older adults. Methods Men and women (ages 45–64 years) from the …
Structural neuroimaging in adults and adolescents with newly diagnosed focal epilepsy: the human epilepsy project
Background and Objectives Identification of an epileptogenic lesion on structural
neuroimaging in individuals with focal epilepsy is important for management and treatment …
neuroimaging in individuals with focal epilepsy is important for management and treatment …
Structural brain network deviations predict recovery after traumatic brain injury
Objective Traumatic brain injury results in diffuse axonal injury and the ensuing maladaptive
alterations in network function are associated with incomplete recovery and persistent …
alterations in network function are associated with incomplete recovery and persistent …