Immunosenescence and its hallmarks: how to oppose aging strategically? A review of potential options for therapeutic intervention
Aging is accompanied by remodeling of the immune system. With time, this leads to a
decline in immune efficacy, resulting in increased vulnerability to infectious diseases …
decline in immune efficacy, resulting in increased vulnerability to infectious diseases …
Inflammaging and oxidative stress in human diseases: from molecular mechanisms to novel treatments
It has been proposed that a chronic state of inflammation correlated with aging known as
inflammaging, is implicated in multiple disease states commonly observed in the elderly …
inflammaging, is implicated in multiple disease states commonly observed in the elderly …
Intermittent and periodic fasting, longevity and disease
Intermittent and periodic fasting (IF and PF, respectively) are emerging as safe strategies to
affect longevity and healthspan by acting on cellular aging and disease risk factors, while …
affect longevity and healthspan by acting on cellular aging and disease risk factors, while …
[HTML][HTML] Dietary intake regulates the circulating inflammatory monocyte pool
Caloric restriction is known to improve inflammatory and autoimmune diseases. However,
the mechanisms by which reduced caloric intake modulates inflammation are poorly …
the mechanisms by which reduced caloric intake modulates inflammation are poorly …
Fasting-mimicking diet modulates microbiota and promotes intestinal regeneration to reduce inflammatory bowel disease pathology
P Rangan, I Choi, M Wei, G Navarrete, E Guen… - Cell reports, 2019 - cell.com
Dietary interventions are potentially effective therapies for inflammatory bowel diseases
(IBDs). We tested the effect of 4-day fasting-mimicking diet (FMD) cycles on a chronic …
(IBDs). We tested the effect of 4-day fasting-mimicking diet (FMD) cycles on a chronic …
[HTML][HTML] Low-carb and ketogenic diets in type 1 and type 2 diabetes
Low-carb and ketogenic diets are popular among clinicians and patients, but the
appropriateness of reducing carbohydrates intake in obese patients and in patients with …
appropriateness of reducing carbohydrates intake in obese patients and in patients with …
Age-related mitochondrial dysfunction as a key factor in COVID-19 disease
DJM Fernández-Ayala, P Navas… - Experimental gerontology, 2020 - Elsevier
SARS-CoV-2 causes a severe pneumonia (COVID-19) that affects essentially elderly
people. In COVID-19, macrophage infiltration into the lung causes a rapid and intense …
people. In COVID-19, macrophage infiltration into the lung causes a rapid and intense …
Boosting NAD+ blunts TLR4-induced type I IFN in control and systemic lupus erythematosus monocytes
J Wu, K Singh, A Lin, AM Meadows… - The Journal of …, 2022 - Am Soc Clin Investig
BACKGROUND Fasting and NAD+-boosting compounds, including NAD+ precursor
nicotinamide riboside (NR), confer antiinflammatory effects. However, the underlying …
nicotinamide riboside (NR), confer antiinflammatory effects. However, the underlying …
Weight loss improves disease activity in patients with psoriatic arthritis and obesity: an interventional study
E Klingberg, A Bilberg, S Björkman, M Hedberg… - Arthritis research & …, 2019 - Springer
Background Obesity is over-represented in patients with psoriatic arthritis (PsA) and
associated with higher disease activity, poorer effect of treatment and increased …
associated with higher disease activity, poorer effect of treatment and increased …
Influence of dietary habits on oxidative stress markers in Hashimoto's thyroiditis
RM Ruggeri, S Giovinazzo, MC Barbalace, M Cristani… - Thyroid, 2021 - liebertpub.com
Background: There is a growing awareness that nutritional habits may influence risk of
several inflammatory and immune-mediated disorders, including autoimmune diseases …
several inflammatory and immune-mediated disorders, including autoimmune diseases …