SARS-CoV-2, COVID-19 and the aging immune system
JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …
particular risk for severe disease and death in older adults and in adults with age-related …
Patients with COVID-19: in the dark-NETs of neutrophils
SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …
Genetic mechanisms of critical illness in COVID-19
Host-mediated lung inflammation is present, and drives mortality, in the critical illness
caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with …
caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with …
NETosis and neutrophil extracellular traps in COVID-19: immunothrombosis and beyond
Y Zhu, X Chen, X Liu - Frontiers in Immunology, 2022 - frontiersin.org
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …
Neutrophil, neutrophil extracellular traps and endothelial cell dysfunction in sepsis
H Zhang, Y Wang, M Qu, W Li, D Wu… - Clinical and …, 2023 - Wiley Online Library
Sepsis is a persistent systemic inflammatory condition involving multiple organ failures
resulting from a dysregulated immune response to infection, and one of the hallmarks of …
resulting from a dysregulated immune response to infection, and one of the hallmarks of …
Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets
Non-human primate models will expedite therapeutics and vaccines for coronavirus disease
2019 (COVID-19) to clinical trials. Here, we compare acute severe acute respiratory …
2019 (COVID-19) to clinical trials. Here, we compare acute severe acute respiratory …
A detailed overview of immune escape, antibody escape, partial vaccine escape of SARS-CoV-2 and their emerging variants with escape mutations
The infective SARS-CoV-2 is more prone to immune escape. Presently, the significant
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …
[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets
M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …
Immune cell dynamics deconvoluted by single-cell RNA sequencing in normothermic machine perfusion of the liver
Normothermic machine perfusion (NMP) has emerged as an innovative organ preservation
technique. Develo** an understanding for the donor organ immune cell composition and …
technique. Develo** an understanding for the donor organ immune cell composition and …
RIG-I-like receptor-mediated recognition of viral genomic RNA of severe acute respiratory syndrome coronavirus-2 and viral escape from the host innate immune …
T Kouwaki, T Nishimura, G Wang… - Frontiers in …, 2021 - frontiersin.org
RIG-I-like receptors (RLR), RIG-I and MDA5, are cytoplasmic viral RNA sensors that
recognize viral double-stranded RNAs and trigger signals to induce antiviral responses …
recognize viral double-stranded RNAs and trigger signals to induce antiviral responses …