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Remission and recovery from first-episode psychosis in adults: systematic review and meta-analysis of long-term outcome studies
BackgroundRemission and recovery rates for people with first-episode psychosis (FEP)
remain uncertain. AimsTo assess pooled prevalence rates of remission and recovery in FEP …
remain uncertain. AimsTo assess pooled prevalence rates of remission and recovery in FEP …
Rethinking schizophrenia
TR Insel - Nature, 2010 - nature.com
How will we view schizophrenia in 2030? Schizophrenia today is a chronic, frequently
disabling mental disorder that affects about one per cent of the world's population. After a …
disabling mental disorder that affects about one per cent of the world's population. After a …
Clinical recovery and long-term association of specialized early intervention services vs treatment as usual among individuals with first-episode schizophrenia …
Importance The OPUS 20-year follow-up is the longest follow-up of a randomized clinical
trial testing early intervention services (EIS) among individuals with first-episode …
trial testing early intervention services (EIS) among individuals with first-episode …
Recovery and serious mental illness: a review of current clinical and research paradigms and future directions
Introduction: Recovery from serious mental illness has historically not been considered a
likely or even possible outcome. However, a range of evidence suggests the courses of SMI …
likely or even possible outcome. However, a range of evidence suggests the courses of SMI …
The myth of schizophrenia as a progressive brain disease
Schizophrenia has historically been considered to be a deteriorating disease, a view
reinforced by recent MRI findings of progressive brain tissue loss over the early years of …
reinforced by recent MRI findings of progressive brain tissue loss over the early years of …
Long-term follow-up of the TIPS early detection in psychosis study: effects on 10-year outcome
WV Hegelstad, TK Larsen, B Auestad… - American Journal of …, 2012 - psychiatryonline.org
Objective: Early detection in first-episode psychosis confers advantages for negative,
cognitive, and depressive symptoms after 1, 2, and 5 years, but longitudinal effects are …
cognitive, and depressive symptoms after 1, 2, and 5 years, but longitudinal effects are …
Long-term trajectories of positive and negative symptoms in first episode psychosis: a 10 year follow-up study in the OPUS cohort
Objective Knowledge about course of illness can help clinicians to develop effective
interventions and improve treatment outcomes. The goal of this study was to construct …
interventions and improve treatment outcomes. The goal of this study was to construct …
Employment and the associated impact on quality of life in people diagnosed with schizophrenia
C Bouwmans, C de Sonneville, CL Mulder… - Neuropsychiatric …, 2015 - Taylor & Francis
A systematic review was conducted to assess the employment rate of people with
schizophrenia. Additionally, information from the selected studies concerning factors …
schizophrenia. Additionally, information from the selected studies concerning factors …
Motivational deficits in early schizophrenia: prevalent, persistent, and key determinants of functional outcome
Negative symptoms, in particular motivational deficits, are reported as impediments to
functional recovery in patients with schizophrenia. This study examined the prevalence of …
functional recovery in patients with schizophrenia. This study examined the prevalence of …
Road to full recovery: longitudinal relationship between symptomatic remission and psychosocial recovery in first-episode psychosis over 7.5 years
M Alvarez-Jimenez, JF Gleeson, LP Henry… - Psychological …, 2012 - cambridge.org
BackgroundIn recent years there has been increasing interest in functional recovery in the
early phase of schizophrenia. Concurrently, new remission criteria have been proposed and …
early phase of schizophrenia. Concurrently, new remission criteria have been proposed and …