Remission and recovery from first-episode psychosis in adults: systematic review and meta-analysis of long-term outcome studies

J Lally, O Ajnakina, B Stubbs, M Cullinane… - The British Journal of …, 2017 - cambridge.org
BackgroundRemission and recovery rates for people with first-episode psychosis (FEP)
remain uncertain. AimsTo assess pooled prevalence rates of remission and recovery in FEP …

Rethinking schizophrenia

TR Insel - Nature, 2010 - nature.com
How will we view schizophrenia in 2030? Schizophrenia today is a chronic, frequently
disabling mental disorder that affects about one per cent of the world's population. After a …

Recovery and serious mental illness: a review of current clinical and research paradigms and future directions

BL Leonhardt, K Huling, JA Hamm, D Roe… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Recovery from serious mental illness has historically not been considered a
likely or even possible outcome. However, a range of evidence suggests the courses of SMI …

The myth of schizophrenia as a progressive brain disease

RB Zipursky, TJ Reilly, RM Murray - Schizophrenia bulletin, 2013 - academic.oup.com
Schizophrenia has historically been considered to be a deteriorating disease, a view
reinforced by recent MRI findings of progressive brain tissue loss over the early years of …

Long-term follow-up of the TIPS early detection in psychosis study: effects on 10-year outcome

WV Hegelstad, TK Larsen, B Auestad… - American Journal of …, 2012 - psychiatryonline.org
Objective: Early detection in first-episode psychosis confers advantages for negative,
cognitive, and depressive symptoms after 1, 2, and 5 years, but longitudinal effects are …

Long-term trajectories of positive and negative symptoms in first episode psychosis: a 10 year follow-up study in the OPUS cohort

SF Austin, O Mors, E Budtz-Jørgensen, RG Secher… - Schizophrenia …, 2015 - Elsevier
Objective Knowledge about course of illness can help clinicians to develop effective
interventions and improve treatment outcomes. The goal of this study was to construct …

Employment and the associated impact on quality of life in people diagnosed with schizophrenia

C Bouwmans, C de Sonneville, CL Mulder… - Neuropsychiatric …, 2015 - Taylor & Francis
A systematic review was conducted to assess the employment rate of people with
schizophrenia. Additionally, information from the selected studies concerning factors …

Motivational deficits in early schizophrenia: prevalent, persistent, and key determinants of functional outcome

G Fervaha, G Foussias, O Agid, G Remington - Schizophrenia research, 2015 - Elsevier
Negative symptoms, in particular motivational deficits, are reported as impediments to
functional recovery in patients with schizophrenia. This study examined the prevalence of …

Road to full recovery: longitudinal relationship between symptomatic remission and psychosocial recovery in first-episode psychosis over 7.5 years

M Alvarez-Jimenez, JF Gleeson, LP Henry… - Psychological …, 2012 - cambridge.org
BackgroundIn recent years there has been increasing interest in functional recovery in the
early phase of schizophrenia. Concurrently, new remission criteria have been proposed and …