[HTML][HTML] Sensory processing sensitivity in the context of environmental sensitivity: A critical review and development of research agenda

CU Greven, F Lionetti, C Booth, EN Aron, E Fox… - Neuroscience & …, 2019 - Elsevier
Abstract Sensory Processing Sensitivity (SPS) is a common, heritable and evolutionarily
conserved trait describing inter-individual differences in sensitivity to both negative and …

SPARK: A US cohort of 50,000 families to accelerate autism research

P Feliciano, AM Daniels, LAG Snyder, A Beaumont… - Neuron, 2018 - cell.com
The Simons Foundation Autism Research Initiative (SFARI) has launched SPARKForAutism.
org, a dynamic platform that is engaging thousands of individuals with autism spectrum …

Rare coding variation provides insight into the genetic architecture and phenotypic context of autism

JM Fu, FK Satterstrom, M Peng, H Brand, RL Collins… - Nature …, 2022 - nature.com
Some individuals with autism spectrum disorder (ASD) carry functional mutations rarely
observed in the general population. We explored the genes disrupted by these variants from …

Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes

X Zhou, P Feliciano, C Shu, T Wang, I Astrovskaya… - Nature …, 2022 - nature.com
To capture the full spectrum of genetic risk for autism, we performed a two-stage analysis of
rare de novo and inherited coding variants in 42,607 autism cases, including 35,130 new …

The contributions of rare inherited and polygenic risk to ASD in multiplex families

M Cirnigliaro, TS Chang, SA Arteaga… - Proceedings of the …, 2023 - National Acad Sciences
Autism spectrum disorder (ASD) has a complex genetic architecture involving contributions
from both de novo and inherited variation. Few studies have been designed to address the …

Modeling idiopathic autism in forebrain organoids reveals an imbalance of excitatory cortical neuron subtypes during early neurogenesis

A Jourdon, F Wu, J Mariani, D Capauto, S Norton… - Nature …, 2023 - nature.com
Idiopathic autism spectrum disorder (ASD) is highly heterogeneous, and it remains unclear
how convergent biological processes in affected individuals may give rise to symptoms …

Human gut microbiota from autism spectrum disorder promote behavioral symptoms in mice

G Sharon, NJ Cruz, DW Kang, MJ Gandal, B Wang… - Cell, 2019 - cell.com
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors
including social communication and stereotypies. In addition to genetic risks, the gut …

Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups

M Mattheisen, J Grove, TD Als, J Martin, G Voloudakis… - Nature Genetics, 2022 - nature.com
Attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are
highly heritable neurodevelopmental conditions, with considerable overlap in their genetic …

Association of genetic and environmental factors with autism in a 5-country cohort

D Bai, BHK Yip, GC Windham, A Sourander… - JAMA …, 2019 - jamanetwork.com
Importance The origins and development of autism spectrum disorder (ASD) remain
unresolved. No individual-level study has provided estimates of additive genetic, maternal …

Multi-trait analysis for genome-wide association study of five psychiatric disorders

Y Wu, H Cao, A Baranova, H Huang, S Li, L Cai… - Translational …, 2020 - nature.com
We conducted a cross-trait meta-analysis of genome-wide association study on
schizophrenia (SCZ)(n= 65,967), bipolar disorder (BD)(n= 41,653), autism spectrum …