In the past decade, an exciting realization has been that diverse liver diseases—ranging
from nonalcoholic steatohepatitis, alcoholic steatohepatitis and cirrhosis to hepatocellular …

Alcoholic liver disease, which ranges from mild disease to alcoholic hepatitis and cirrhosis,
is a leading cause of morbidity and mortality worldwide. Alcohol intake can lead to changes …

Alcoholism is a widespread and damaging behaviour of people throughout the world. Long-
term alcohol consumption has resulted in alcoholic liver disease (ALD) being the leading …

Humans consider themselves discrete autonomous organisms, but recent research is
rapidly strengthening the appreciation that associated microorganisms make essential …

Circadian rhythms are 24-h patterns regulating behavior, organs, and cells in living
organisms. These rhythms align biological functions with regular and predictable …

Nowadays, melatonin, previously considered only as a pharmaceutical product for rhythm
regulation and sleep aiding, has shown its potential as a co‐adjuvant treatment in intestinal …

Transmission and secretion of signals via the choroid plexus (ChP) brain barrier can
modulate brain states via regulation of cerebrospinal fluid (CSF) composition. Here, we …

Sleep disorders have received widespread attention nowadays, which have been promoted
by the accelerated pace of life, unhealthy diets and lack of exercise in modern society. The …

Both chronic and acute (binge) alcohol drinking are important health and economic
concerns worldwide and prominent risk factors for the development of alcoholic liver disease …

Alcohol consumption is known to cause several brain anomalies. The pathophysiological
changes associated with alcohol intoxication are mediated by various factors, most notable …