Over the past 10 years, the drive to improve outcomes from epilepsy surgery has stimulated
widespread interest in methods to quantitatively guide epilepsy surgery from intracranial …

Decades of rodent research have established the role of hippocampal sharp wave ripples
(SPW-Rs) in consolidating and guiding experience. More recently, intracranial recordings in …

Working memory is thought to result from sustained neuron spiking. However, computational
models suggest complex dynamics with discrete oscillatory bursts. We analyzed local field …

A postulated role of subcortical neuromodulators is to control brain states. Mechanisms by
which different neuromodulators compete or cooperate at various temporal scales remain an …

Planning surgery for patients with medically refractory epilepsy often requires recording
seizures using intracranial EEG. Quantitative measures derived from interictal intracranial …

High‐frequency oscillations (HFO s) are a type of brain activity that is recorded from brain
regions capable of generating seizures. Because of the close association of HFO s with …

Broadband high-frequency activity (BHA; 70 to 150 Hz), also known as “high gamma,” a key
analytic signal in human intracranial (electrocorticographic) recordings, is often assumed to …

Neuronal signalling is a key element in neuronal communication and is essential for the
proper functioning of the CNS. Astrocytes, the most prominent glia in the brain play a key …

Macroscopic neural dynamics comprise both aperiodic and periodic signal components.
Recent advances in parameterizing neural power spectra offer practical tools for evaluating …

The study of sharp-wave ripples has advanced our understanding of memory function, and
their alteration in neurological conditions such as epilepsy is considered a biomarker of …