The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology
The current coronavirus disease 2019 (COVID-19) pandemic is the first to apply whole-
genome sequencing near to real time, with over 2 million severe acute respiratory syndrome …
genome sequencing near to real time, with over 2 million severe acute respiratory syndrome …
The disease severity and clinical outcomes of the SARS-CoV-2 variants of concern
With the continuation of the pandemic, many severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) variants have appeared around the world. Owing to a possible risk of …
2 (SARS-CoV-2) variants have appeared around the world. Owing to a possible risk of …
BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans
U Sahin, A Muik, I Vogler, E Derhovanessian, LM Kranz… - Nature, 2021 - nature.com
Abstract BNT162b2, a nucleoside-modified mRNA formulated in lipid nanoparticles that
encodes the SARS-CoV-2 spike glycoprotein (S) stabilized in its prefusion conformation, has …
encodes the SARS-CoV-2 spike glycoprotein (S) stabilized in its prefusion conformation, has …
SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients
The emergence of SARS-CoV-2 variants harboring mutations in the spike (S) protein has
raised concern about potential immune escape. Here, we studied humoral and cellular …
raised concern about potential immune escape. Here, we studied humoral and cellular …
Assessing transmissibility of SARS-CoV-2 lineage B. 1.1. 7 in England
Abstract The SARS-CoV-2 lineage B. 1.1. 7, designated variant of concern (VOC) 202012/01
by Public Health England, was first identified in the UK in late summer to early autumn 2020 …
by Public Health England, was first identified in the UK in late summer to early autumn 2020 …
Genomics and epidemiology of the P. 1 SARS-CoV-2 lineage in Manaus, Brazil
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in
Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome …
Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome …
SARS-CoV-2 immune evasion by the B. 1.427/B. 1.429 variant of concern
A novel variant of concern (VOC) named CAL. 20C (B. 1.427/B. 1.429), which was originally
detected in California, carries spike glycoprotein mutations S13I in the signal peptide …
detected in California, carries spike glycoprotein mutations S13I in the signal peptide …
Sensitivity of infectious SARS-CoV-2 B. 1.1. 7 and B. 1.351 variants to neutralizing antibodies
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B. 1.1. 7 and B. 1.351
variants were first identified in the United Kingdom and South Africa, respectively, and have …
variants were first identified in the United Kingdom and South Africa, respectively, and have …
[HTML][HTML] Increased resistance of SARS-CoV-2 variant P. 1 to antibody neutralization
The emergence of SARS-CoV-2 variants has raised concerns about altered sensitivity to
antibody-mediated immunity. The relative resistance of SARS-CoV-2 variants B. 1.1. 7 and …
antibody-mediated immunity. The relative resistance of SARS-CoV-2 variants B. 1.1. 7 and …
Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission leads to the
emergence of variants, including the B. 1.617. 2 (Delta) variant of concern that is causing a …
emergence of variants, including the B. 1.617. 2 (Delta) variant of concern that is causing a …