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[HTML][HTML] Ferroptosis: A novel therapeutic target of natural products against doxorubicin-induced cardiotoxicity
X Yi, Q Wang, M Zhang, Q Shu, J Zhu - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Doxorubicin (DOX), a commonly used chemotherapy drug, is hindered due to its tendency to
induce cardiotoxicity (DIC). Ferroptosis, a novel mode of programmed cell death, has …
induce cardiotoxicity (DIC). Ferroptosis, a novel mode of programmed cell death, has …
Iron homeostasis and ferroptosis in muscle diseases and disorders: mechanisms and therapeutic prospects
The muscular system plays a critical role in the human body by governing skeletal
movement, cardiovascular function, and the activities of digestive organs. Additionally …
movement, cardiovascular function, and the activities of digestive organs. Additionally …
[HTML][HTML] Restoring bone-fat equilibrium: Baicalin's impact on P38 MAPK pathway for treating diabetic osteoporosis
Diabetes can lead to a disorder of bone-fat balance, a significant cause of osteoporosis due
to changes in environmental factors. Baicalin (Bai), an active ingredient of Scutellaria …
to changes in environmental factors. Baicalin (Bai), an active ingredient of Scutellaria …
Control the Gene Delivery and Anticancer Efficacy of Peptides through Chiral Modulation
Z Wang, L Yue, J Min, H Liu, Y Zhang, Y Du, R Su… - Nano Letters, 2025 - ACS Publications
Incorporating d-amino acids into peptides can influence the intermolecular interactions of
peptides, thus determining the morphology and functionality of self-assembled …
peptides, thus determining the morphology and functionality of self-assembled …
Baicalin nanofiber membranes: A comprehensive study on preparation, characterization, and antimicrobial pharmacological activities
W Hou, W Guo, Z Dai, H Ren, X Luo, J Fu - Journal of Molecular Structure, 2025 - Elsevier
Baicalin is a natural active ingredient known for its medicinal properties and a broad
spectrum of pharmacological activities, including antimicrobial, antioxidant, antiviral, and …
spectrum of pharmacological activities, including antimicrobial, antioxidant, antiviral, and …
[HTML][HTML] Flavonoids for gastrointestinal tract local and associated systemic effects: A review of clinical trials and future perspectives
X Li, E **e, S Sun, J Shen, Y Ding, J Wang… - Journal of Advanced …, 2025 - Elsevier
Background Flavonoids are naturally occurring dietary phytochemicals with significant
antioxidant effects aside from several health benefits. People often consume them in …
antioxidant effects aside from several health benefits. People often consume them in …
Ferroptosis: Latest evidence and perspectives on plant‐derived natural active compounds mitigating doxorubicin‐induced cardiotoxicity
B Wang, J Wang, C Liu, C Li, T Meng… - Journal of Applied …, 2025 - Wiley Online Library
Doxorubicin (DOX) is a chemotherapy drug widely used in clinical settings, acting as a first‐
line treatment for various malignant tumors. However, its use is greatly limited by the …
line treatment for various malignant tumors. However, its use is greatly limited by the …
Cancer-targeting drug conjugates drives a new era in precise cancer treatment
J Deng, J Shi, D Li, X Jiao, J Liu, H Tian, N Liu… - Chinese Chemical …, 2025 - Elsevier
Cancer is the second leading cause of death globally. Its treatment remains a major
challenge due to the disease's complexity, heterogeneity, and adaptive nature. Among the …
challenge due to the disease's complexity, heterogeneity, and adaptive nature. Among the …
Peptide-Amphiphilic Nanoassemblies as a Responsive Senolytic Navigator for Targeted Removal of Senescent Cardiomyocytes to Ameliorate Heart Failure
Z Wu, Y Zeng, H Chen, Z **ao, J Guo… - … Applied Materials & …, 2024 - ACS Publications
Heart failure (HF) represents the terminal stage of numerous cardiovascular disorders and
lacks effective therapeutic strategies. The accumulation of senescent cardiomyocytes is a …
lacks effective therapeutic strategies. The accumulation of senescent cardiomyocytes is a …
Myocardium-targeted liposomal delivery of the antioxidant peptide 8P against doxorubicin-induced myocardial injury
M Zhao, C Liu, Z Liu, Y Zuo, C Chen, S Shi… - International Journal of …, 2024 - Elsevier
Doxorubicin (Dox) is a broad-spectrum antineoplastic chemotherapeutic agent used in
clinical settings, yet it exhibits significant cardiotoxicity, which in severe cases can lead to …
clinical settings, yet it exhibits significant cardiotoxicity, which in severe cases can lead to …