Proton beam range verification by means of ionoacoustic measurements at clinically relevant doses using a correlation-based evaluation

J Schauer, HP Wieser, Y Huang, H Ruser… - Frontiers in …, 2022 - frontiersin.org
Purpose The Bragg peak located at the end of the ion beam range is one of the main
advantages of ion beam therapy compared to X-Ray radiotherapy. However, verifying the …

Laser-driven x-ray and proton micro-source and application to simultaneous single-shot bi-modal radiographic imaging

TM Ostermayr, C Kreuzer, FS Englbrecht… - Nature …, 2020 - nature.com
Radiographic imaging with x-rays and protons is an omnipresent tool in basic research and
applications in industry, material science and medical diagnostics. The information …

Time-of-flight spectroscopy for laser-driven proton beam monitoring

M Reimold, S Assenbaum, C Bernert, E Beyreuther… - Scientific Reports, 2022 - nature.com
Application experiments with laser plasma-based accelerators (LPA) for protons have to
cope with the inherent fluctuations of the proton source. This creates a demand for non …

Experimental demonstration of accurate Bragg peak localization with ionoacoustic tandem phase detection (iTPD)

HP Wieser, Y Huang, J Schauer… - Physics in Medicine …, 2021 - iopscience.iop.org
Accurate knowledge of the exact stop** location of ions inside the patient would allow full
exploitation of their ballistic properties for patient treatment. The localized energy deposition …

OCTOPOD: single-bunch tomography for angular-spectral characterization of laser-driven protons

M Reimold, S Assenbaum, E Beyreuther… - High Power Laser …, 2023 - cambridge.org
Laser–plasma accelerated (LPA) proton bunches are now applied for research fields
ranging from ultra-high-dose-rate radiobiology to material science. Yet, the capabilities to …

On the robustness of multilateration of ionoacoustic signals for localization of the Bragg peak at pre-clinical proton beam energies in water

R Kalunga, HP Wieser, P Dash, M Würl… - Physics in Medicine …, 2023 - iopscience.iop.org
Objectives. The energy deposited in a medium by a pulsed proton beam results in the
emission of thermoacoustic waves, also called ionoacoustics (IA). The proton beam stop** …

Enhancement of the ionoacoustic effect through ultrasound and photoacoustic contrast agents

J Lascaud, P Dash, M Würl, HP Wieser, B Wollant… - Scientific reports, 2021 - nature.com
The characteristic depth dose deposition of ion beams, with a maximum at the end of their
range (Bragg peak) allows for local treatment delivery, resulting in better sparing of the …

[HTML][HTML] A Monte Carlo feasibility study on quantitative laser-driven proton radiography

M Würl, C Gianoli, FS Englbrecht, J Schreiber… - … für Medizinische Physik, 2022 - Elsevier
Laser-accelerated proton bunches with kinetic energies up to several tens of MeV and at
repetition rates in the order of Hz are nowadays achievable at several research centres …

Beam monitoring and dosimetry for ultra-high dose rate radiobiology at laser-driven proton sources

M Reimold - 2024 - tud.qucosa.de
Abstract (EN) Ultra-high dose rate proton radiation has the potential to improve cancer
treatment by reducing the normal tissue complication probability and, at the same time …