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[HTML][HTML] Keratin 6, 16 and 17—critical barrier alarmin molecules in skin wounds and psoriasis
Located at the skin surface, keratinocytes (KCs) are constantly exposed to external stimuli
and are the first responders to invading pathogens and injury. Upon skin injury, activated …
and are the first responders to invading pathogens and injury. Upon skin injury, activated …
Interleukin-17A and keratinocytes in psoriasis
The excellent clinical efficacy of anti-interleukin 17A (IL-17A) biologics on psoriasis indicates
a crucial pathogenic role of IL-17A in this autoinflammatory skin disease. IL-17A accelerates …
a crucial pathogenic role of IL-17A in this autoinflammatory skin disease. IL-17A accelerates …
The human keratins: biology and pathology
R Moll, M Divo, L Langbein - Histochemistry and cell biology, 2008 - Springer
The keratins are the typical intermediate filament proteins of epithelia, showing an
outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing …
outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing …
Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia
HH Bragulla, DG Homberger - Journal of anatomy, 2009 - Wiley Online Library
Historically, the term 'keratin'stood for all of the proteins extracted from skin modifications,
such as horns, claws and hooves. Subsequently, it was realized that this keratin is actually a …
such as horns, claws and hooves. Subsequently, it was realized that this keratin is actually a …
IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes
K Boniface, FX Bernard, M Garcia… - The Journal of …, 2005 - journals.aai.org
IL-22 belongs to a family of cytokines structurally related to IL-10, including IL-19, IL-20, IL-
24, and IL-26. In contrast to IL-10, IL-22 has proinflammatory activities. IL-22 signals through …
24, and IL-26. In contrast to IL-10, IL-22 has proinflammatory activities. IL-22 signals through …
'Hard'and 'soft'principles defining the structure, function and regulation of keratin intermediate filaments
Keratins make up the largest subgroup of intermediate filament proteins and represent the
most abundant proteins in epithelial cells. They exist as highly dynamic networks of …
most abundant proteins in epithelial cells. They exist as highly dynamic networks of …
Nestin is required for the proper self-renewal of neural stem cells
The intermediate filament protein, nestin, is a widely employed marker of multipotent neural
stem cells (NSCs). Recent in vitro studies have implicated nestin in a number of cellular …
stem cells (NSCs). Recent in vitro studies have implicated nestin in a number of cellular …
[PDF][PDF] Therapeutic effects of topical application of ozone on acute cutaneous wound healing
HS Kim, SU Noh, YW Han, KM Kim… - Journal of Korean …, 2009 - synapse.koreamed.org
This study was undertaken to evaluate the therapeutic effects of topical ozonated olive oil on
acute cutaneous wound healing in a guinea pig model and also to elucidate its therapeutic …
acute cutaneous wound healing in a guinea pig model and also to elucidate its therapeutic …
Biological importance and pharmaceutical significance of keratin: a review
Protein-based biomaterials have emerged as a promising alternative because of their
inherent cell-to-cell interaction, structural support, and cellular communications. Over the last …
inherent cell-to-cell interaction, structural support, and cellular communications. Over the last …
Epithelial structural proteins of the skin and oral cavity: function in health and disease
Epithelial tissues function to protect the organism from physical, chemical, and microbial
damage and are essential for survival. To perform this role, epithelial keratinocytes undergo …
damage and are essential for survival. To perform this role, epithelial keratinocytes undergo …