The innate immune response provides the first line of defense against invading pathogens,
and immune disorders cause a variety of diseases. The fruit fly Drosophila melanogaster …

The spatio-temporal regulation of gene expression determines the fate and function of
various cells and tissues and, as a consequence, the correct development and functioning of …

SARS-CoV-2 infection causes COVID-19, a severe acute respiratory disease associated
with cardiovascular complications including long-term outcomes. The presence of virus in …

Development of effective therapies against SARS-CoV-2 infections relies on mechanistic
knowledge of virus-host interface. Abundant physical interactions between viral and host …

An overarching goal of aging and age-related neurodegenerative disease research is to
discover effective therapeutic strategies applicable to a broad spectrum of …

Bacteria from the genus Providencia are ubiquitous Gram-negative opportunistic pathogens,
causing “travelers' diarrhea”, urinary tract, and other nosocomial infections in humans. Some …

Insects occupy a central position in the biosphere. They are able to resist infections even
though they lack an adaptive immune system. Drosophila melanogaster has been used as a …

Genome-wide association studies have advanced our understanding of complex traits, but
studying how a GWAS variant can affect a specific trait in the human population remains …

The dimeric cytokine ligand Spätzle (Spz) is responsible for Toll pathway activation and
antimicrobial peptide (AMP) production upon pathogen challenge in Tenebrio molitor. Here …

Steinernema carpocapsae is an entomopathogenic nematode (EPN) that rapidly infects and
kills a wide range of insect hosts and has been linked to host immunosuppression during the …