Cushing's disease requires accurate diagnosis, careful treatment selection, and long-term
management to optimise patient outcomes. The Pituitary Society convened a consensus …

Importance Pituitary adenomas may hypersecrete hormones or cause mass effects.
Therefore, early diagnosis and treatment are important. Observations Prevalence of pituitary …

Abstract Cushing's disease (CD), or pituitary-dependent Cushing's syndrome, is a severe
endocrine disease caused by a corticotroph pituitary tumor and associated with increased …

To study the currently available data of recurrence rates of functioning and nonfunctioning
pituitary adenomas following surgical cure and to analyze associated predisposing factors …

Cushing's disease (CD) is the result of excess secretion of adrenocorticotropic hormone
(ACTH) by a benign monoclonal pituitary adenoma. The excessive secretion of ACTH …

Background: The use of ketoconazole has been recently questioned after warnings from the
European Medicine Agencies and the Food and Drug Administration due to potential …

Objective Cushing's disease (CD) is a rare endocrine disorder characterized by excess
secretion of ACTH due to a pituitary adenoma. Current treatment options are limited and …

Context: We have recently reported somatic mutations in the ubiquitin-specific protease
USP8 gene in a small series of adenomas of patients with Cushing's disease. Objective: To …

Background: The outcome of bilateral adrenalectomy (BADx) in patients with Cushing's
syndrome (CS) is not well characterized. Methods: A literature search was performed with …

Overt Cushing's syndrome is a rare disorder with an annual incidence of 2–3/million of
which benign adrenal adenomas account for 0.6/million. The female: male ratio is 3: 1 …