[HTML][HTML] Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration

S Lyu, Z Dong, X Xu, HP Bei, HY Yuen, CWJ Cheung… - Bioactive materials, 2023‏ - Elsevier
Microneedle, as a novel drug delivery system, has attracted widespread attention due to its
non-invasiveness, painless and simple administration, controllable drug delivery, and …

The role of 3D printing technology in microengineering of microneedles

U Detamornrat, E McAlister, ARJ Hutton, E Larrañeta… - Small, 2022‏ - Wiley Online Library
Microneedles (MNs) are minimally invasive devices, which have gained extensive interest
over the past decades in various fields including drug delivery, disease diagnosis …

Catheter-integrated soft multilayer electronic arrays for multiplexed sensing and actuation during cardiac surgery

M Han, L Chen, K Aras, C Liang, X Chen… - Nature biomedical …, 2020‏ - nature.com
The rigidity and relatively primitive modes of operation of catheters equipped with sensing or
actuation elements impede their conformal contact with soft-tissue surfaces, limit the scope …

Microneedle biomedical devices

M Zheng, T Sheng, J Yu, Z Gu, C Xu - Nature Reviews Bioengineering, 2024‏ - nature.com
Microneedle (MN) technologies have gained interest for biomedical applications, ranging
from drug delivery to sensing and tissue sampling in skin and internal organs. The …

Biodegradable microneedles fabricated with carbohydrates and proteins: Revolutionary approach for transdermal drug delivery

N Dabholkar, S Gorantla, T Waghule, VK Rapalli… - International Journal of …, 2021‏ - Elsevier
There has been a surge in the use of transdermal drug delivery systems (TDDS) for the past
few years. The market of TDDS is expected to reach USD 7.1 billion by 2023, from USD 5.7 …

[HTML][HTML] Smart microneedles for therapy and diagnosis

X Zhang, Y Wang, J Chi, Y Zhao - Research, 2020‏ - spj.science.org
Microneedles represent a cutting-edge and idea-inspiring technology in biomedical
engineering, which have attracted increasing attention of scientific researchers and medical …

Soft bioelectronics for heart monitoring

H Mirzajani, M Kraft - Acs Sensors, 2024‏ - ACS Publications
Cardiovascular diseases (CVDs) are a predominant global health concern, accounting for
over 17.9 million deaths in 2019, representing approximately 32% of all global fatalities. In …

Recent strategies for improving hemocompatibility and endothelialization of cardiovascular devices and inhibition of intimal hyperplasia

LA Feng, J Shi, JY Guo, SF Wang - Journal of Materials Chemistry B, 2022‏ - pubs.rsc.org
Cardiovascular diseases have become one of the leading causes of mortality worldwide.
Stents and artificial grafts have been used to treat cardiovascular diseases. Thrombosis and …

Microneedle-mediated transdermal nanodelivery systems: a review

S Ruan, Y Zhang, N Feng - Biomaterials Science, 2021‏ - pubs.rsc.org
The greatest limitation in the development of transdermal drug delivery systems is that only a
few drugs can permeate the skin due to the barrier function of the stratum corneum. Active …

Advances in Polysaccharide-Based Microneedle Systems for the Treatment of Ocular Diseases

Q Bao, X Zhang, Z Hao, Q Li, F Wu, K Wang, Y Li… - Nano-Micro Letters, 2024‏ - Springer
The eye, a complex organ isolated from the systemic circulation, presents significant drug
delivery challenges owing to its protective mechanisms, such as the blood-retinal barrier …