[HTML][HTML] Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration

K Kaarniranta, H Uusitalo, J Blasiak… - Progress in retinal and …, 2020 - Elsevier
Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is considered to
be a key factor in age-related macular degeneration (AMD) pathology. RPE cells are …

Opportunities and challenges of macrogenetic studies

DM Leigh, CB van Rees, KL Millette, MF Breed… - Nature Reviews …, 2021 - nature.com
The rapidly emerging field of macrogenetics focuses on analysing publicly accessible
genetic datasets from thousands of species to explore large-scale patterns and predictors of …

Mitochondrial heterogeneity in diseases

L Chen, M Zhou, H Li, D Liu, P Liao, Y Zong… - … and Targeted Therapy, 2023 - nature.com
As key organelles involved in cellular metabolism, mitochondria frequently undergo
adaptive changes in morphology, components and functions in response to various …

Complete vertebrate mitogenomes reveal widespread repeats and gene duplications

G Formenti, A Rhie, J Balacco, B Haase, J Mountcastle… - Genome biology, 2021 - Springer
Background Modern sequencing technologies should make the assembly of the relatively
small mitochondrial genomes an easy undertaking. However, few tools exist that address …

A lethal mitonuclear incompatibility in complex I of natural hybrids

BM Moran, CY Payne, DL Powell, ENK Iverson… - Nature, 2024 - nature.com
The evolution of reproductive barriers is the first step in the formation of new species and
can help us understand the diversification of life on Earth. These reproductive barriers often …

High resolution DNA barcode library for European butterflies reveals continental patterns of mitochondrial genetic diversity

V Dincă, L Dapporto, P Somervuo, R Vodă… - Communications …, 2021 - nature.com
The study of global biodiversity will greatly benefit from access to comprehensive DNA
barcode libraries at continental scale, but such datasets are still very rare. Here, we …

Genome resequencing reveals rapid, repeated evolution in the Colorado potato beetle

B Pélissié, YH Chen, ZP Cohen… - Molecular Biology …, 2022 - academic.oup.com
Insecticide resistance and rapid pest evolution threatens food security and the development
of sustainable agricultural practices, yet the evolutionary mechanisms that allow pests to …

Inheritance through the cytoplasm

MF Camus, B Alexander-Lawrie, J Sharbrough… - Heredity, 2022 - nature.com
Most heritable information in eukaryotic cells is encoded in the nuclear genome, with
inheritance patterns following classic Mendelian segregation. Genomes residing in the …

Urbanization shapes the ecology and evolution of plant-arthropod herbivore interactions

LS Miles, ST Breitbart, HH Wagner… - Frontiers in Ecology and …, 2019 - frontiersin.org
Urbanization is quickly changing natural and agricultural landscapes, with consequences for
the herbivorous arthropods dwelling in or near cities. Here, we review the evidence for the …

The determinants of genetic diversity in butterflies

A Mackintosh, DR Laetsch, A Hayward… - Nature …, 2019 - nature.com
Under the neutral theory, genetic diversity is expected to increase with population size.
While comparative analyses have consistently failed to find strong relationships between …