The bioavailability, transport, and bioactivity of dietary flavonoids: A review from a historical perspective

G Williamson, CD Kay, A Crozier - Comprehensive Reviews in …, 2018 - Wiley Online Library
Flavonoids are plant‐derived dietary components with a substantial impact on human
health. Research has expanded massively since it began in the 1930s, and the complex …

Polyphenols: From theory to practice

A Bertelli, M Biagi, M Corsini, G Baini, G Cappellucci… - Foods, 2021 - mdpi.com
Background: The importance of polyphenols in human health is well known; these
compounds are common in foods, such as fruits, vegetables, spices, extra virgin olive oil and …

Resveratrol: An overview of its anti-cancer mechanisms

M Elshaer, Y Chen, XJ Wang, X Tang - Life sciences, 2018 - Elsevier
Cancer is one of the leading causes of death worldwide. Chemotherapy and radiotherapy
are the conventional primary treatments for cancer patients. However, most of cancer cells …

Role of endoplasmic reticulum stress in the anticancer activity of natural compounds

P Limonta, RM Moretti, M Marzagalli, F Fontana… - International journal of …, 2019 - mdpi.com
Cancer represents a serious global health problem, and its incidence and mortality are
rapidly growing worldwide. One of the main causes of the failure of an anticancer treatment …

Structural degradation and uptake of resveratrol-encapsulated liposomes using an in vitro digestion combined with Caco-2 cell absorption model

X Xu, M Tian, L Deng, H Jiang, J Han, C Zhen, L Huang… - Food Chemistry, 2023 - Elsevier
Resveratrol (RES), a polyphenol with strong antioxidant capacity but poor bioavailability and
light instability, urgently needs an effective delivery technique to overcome its drawbacks. As …

Nanotechnology advances towards development of targeted-treatment for obesity

NRS Sibuyi, KL Moabelo, M Meyer, MO Onani… - Journal of …, 2019 - Springer
Obesity through its association with type 2 diabetes (T2D), cancer and cardiovascular
diseases (CVDs), poses a serious health threat, as these diseases contribute to high …

Resveratrol Analogues as Selective Estrogen Signaling Pathway Modulators: Structure–Activity Relationship

P Kobylka, M Kucinska, J Kujawski, D Lazewski… - Molecules, 2022 - mdpi.com
Resveratrol is a plant-derived phytoalexin found in grapes, red wine and many other plants
used in Asian folk medicine. It is extensively studied for pleiotropic biological activity. The …

Folic acid-poly (N-isopropylacrylamide-maltodextrin) nanohydrogels as novel thermo-/pH-responsive polymer for resveratrol breast cancer targeted therapy

ORM Metawea, M Teleb, NS Haiba, AO Elzoghby… - European Polymer …, 2023 - Elsevier
Background The long-term sequelae and serious side effects of conventional breast cancer
chemotherapy due to ubiquitous biodistribution and systemic toxicity remain the main …

Resveratrol butyrate esters inhibit BPA-induced liver damage in male offspring rats by modulating antioxidant capacity and gut microbiota

JX Liao, YW Chen, MK Shih, YL Tain, YT Yeh… - International Journal of …, 2021 - mdpi.com
Resveratrol can affect the physiology or biochemistry of offspring in the maternal–fetal
animal model. However, it exhibits low bioavailability in humans and animals. Fifteen-week …

Red wine, resveratrol and atrial fibrillation

LS Stephan, ED Almeida, MM Markoski, J Garavaglia… - Nutrients, 2017 - mdpi.com
Atrial fibrillation (AF) is a common cardiac arrhythmia that is associated with increased risk
for cardiovascular disease and overall mortality. Excessive alcohol intake is a well-known …