The sympathetic nervous system in development and disease

E Scott-Solomon, E Boehm, R Kuruvilla - Nature Reviews …, 2021 - nature.com
The sympathetic nervous system prepares the body for 'fight or flight'responses and
maintains homeostasis during daily activities such as exercise, eating a meal or regulation …

Branch management: mechanisms of axon branching in the develo** vertebrate CNS

K Kalil, EW Dent - Nature Reviews Neuroscience, 2014 - nature.com
The remarkable ability of a single axon to extend multiple branches and form terminal arbors
enables vertebrate neurons to integrate information from divergent regions of the nervous …

Wnt5a–Ror–Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis

HYH Ho, MW Susman, JB Bikoff… - Proceedings of the …, 2012 - National Acad Sciences
Wnts make up a large family of extracellular signaling molecules that play crucial roles in
development and disease. A subset of noncanonical Wnts signal independently of the …

WNT signaling in neuronal maturation and synaptogenesis

SB Rosso, NC Inestrosa - Frontiers in cellular neuroscience, 2013 - frontiersin.org
The Wnt signaling pathway plays a role in the development of the central nervous system
and growing evidence indicates that Wnts also regulates the structure and function of the …

WNT-5A: signaling and functions in health and disease

K Kumawat, R Gosens - Cellular and Molecular Life Sciences, 2016 - Springer
WNT-5A plays critical roles in a myriad of processes from embryonic morphogenesis to the
maintenance of post-natal homeostasis. WNT-5A knock-out mice fail to survive and present …

Wnt signalling in neuronal differentiation and development

NC Inestrosa, L Varela-Nallar - Cell and tissue research, 2015 - Springer
Wnts are secreted glycoproteins that play multiple roles in early development, including the
differentiation of precursor cells. During this period, gradients of Wnts and other morphogens …

SGLT2 inhibitors: A novel therapy for cognitive impairment via multifaceted effects on the nervous system

J Mei, Y Li, L Niu, R Liang, M Tang, Q Cai, J Xu… - Translational …, 2024 - Springer
The rising prevalence of diabetes mellitus has casted a spotlight on one of its significant
sequelae: cognitive impairment. Sodium-glucose cotransporter-2 (SGLT2) inhibitors …

Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses

L Varela-Nallar, IE Alfaro, FG Serrano… - Proceedings of the …, 2010 - National Acad Sciences
Growing evidence indicates that Wingless-type (Wnt) signaling plays an important role in the
maturation of the central nervous system. We report here that Wingless-type family member …

Developmental regulation of axon branching in the vertebrate nervous system

DA Gibson, L Ma - Development, 2011 - journals.biologists.com
During nervous system development, axons generate branches to connect with multiple
synaptic targets. As with axon growth and guidance, axon branching is tightly controlled in …

Mechanisms of neurotrophin trafficking via Trk receptors

E Scott-Solomon, R Kuruvilla - Molecular and Cellular Neuroscience, 2018 - Elsevier
In neurons, long-distance communication between axon terminals and cell bodies is a
critical determinant in establishing and maintaining neural circuits. Neurotrophins are …