Recent advances in understanding the antibacterial properties of flavonoids

TPT Cushnie, AJ Lamb - International journal of antimicrobial agents, 2011 - Elsevier
Antibiotic resistance is a major global problem and there is a pressing need to develop new
therapeutic agents. Flavonoids are a family of plant-derived compounds with potentially …

Comprehensive review in current developments of imidazole‐based medicinal chemistry

L Zhang, XM Peng, GLV Damu… - Medicinal research …, 2014 - Wiley Online Library
Imidazole ring is an important five‐membered aromatic heterocycle widely present in natural
products and synthetic molecules. The unique structural feature of imidazole ring with …

Phenolic Compounds Diminish Antibiotic Resistance of Staphylococcus Aureus Clinical Strains

M Miklasińska-Majdanik, M Kępa… - International journal of …, 2018 - mdpi.com
There is a growing body of evidence that flavonoids show antibacterial activity against both
Gram-positive and Gram-negative bacteria. The mechanisms of action of phenolic …

Recent researches in triazole compounds as medicinal drugs

C -H. Zhou, Y Wang - Current medicinal chemistry, 2012 - benthamdirect.com
Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …

Synthesis and pharmacological properties of chalcones: a review

SL Gaonkar, UN Vignesh - Research on chemical intermediates, 2017 - Springer
Chalcones and their analogs have been an area of great interest in recent years. Numerous
research papers have been published, and chalcones continue to show promise for new …

Trends in utilization of the pharmacological potential of chalcones

DI Batovska, IT Todorova - Current clinical pharmacology, 2010 - ingentaconnect.com
Chalcones (1, 3-diaryl-2-propen-1-ones) are open chain flavonoids that are widely
biosynthesized in plants. They are important for the pigmentation of flowers and, hence, act …

Structure–activity relationship of antibacterial chalcones

HP Ávila, EFA Smânia, F Delle Monache… - Bioorganic & medicinal …, 2008 - Elsevier
The antibacterial activity of 31 chalcones was tested against bacterial strains, Bacillus
cereus ATCC 11778, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC …

Brazilian red propolis: unreported substances, antioxidant and antimicrobial activities

AA Righi, TR Alves, G Negri… - Journal of the …, 2011 - Wiley Online Library
BACKGROUND: Chloroform, ethyl acetate and methanol extracts of a sample of red propolis
from the state of Alagoas (northeast Brazil) were analyzed by gas chromatography–mass …

Significance of chalcone scaffolds in medicinal chemistry

R Mazumder, Ichudaule, A Ghosh, S Deb… - Topics in Current …, 2024 - Springer
Chalcone is a simple naturally occurring α, β-unsaturated ketone with biological importance,
which can also be easily synthesized in laboratories by reaction between two aromatic …

Synthetic flavonoids with antimicrobial activity: a review

LG Sarbu, LG Bahrin, C Babii, M Stefan… - Journal of applied …, 2019 - academic.oup.com
The emergence of drug‐resistant microbes left us with a great need for new antimicrobial
agents. Flavonoids, with their wide range of biological activities, are good candidates in this …