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Mechanisms of stereodirecting participation and ester migration from near and far in glycosylation and related reactions
AA Hettikankanamalage, R Lassfolk, FS Ekholm… - Chemical …, 2020 - ACS Publications
This review is the counterpart of a 2018 Chemical Reviews article (Adero, PO; Amarasekara,
H.; Wen, P.; Bohé, L.; Crich, D. Chem. Rev. 2018, 118, 8242–8284) that examined the …
H.; Wen, P.; Bohé, L.; Crich, D. Chem. Rev. 2018, 118, 8242–8284) that examined the …
The Experimental Evidence in Support of Glycosylation Mechanisms at the SN1–SN2 Interface
A critical review of the state-of-the-art evidence in support of the mechanisms of
glycosylation reactions is provided. Factors affecting the stability of putative oxocarbenium …
glycosylation reactions is provided. Factors affecting the stability of putative oxocarbenium …
En route to the transformation of glycoscience: A chemist's perspective on internal and external crossroads in glycochemistry
D Crich - Journal of the American Chemical Society, 2020 - ACS Publications
Carbohydrate chemistry is an essential component of the glycosciences and is fundamental
to their progress. This Perspective takes the position that carbohydrate chemistry, or …
to their progress. This Perspective takes the position that carbohydrate chemistry, or …
Trifluoromethanesulfonate Anion as Nucleophile in Organic Chemistry
Although the triflate ion is not generally perceived as a nucleophile, many examples of its
behavior as such exist in the literature. This Synopsis presents an overview of such …
behavior as such exist in the literature. This Synopsis presents an overview of such …
Advanced chemical methods for stereoselective sialylation and their applications in sialoglycan syntheses
AM Vibhute, N Komura, HN Tanaka… - The Chemical …, 2021 - Wiley Online Library
Sialic acid is an important component of cell surface glycans, which are responsible for
many vital body functions and should therefore be thoroughly studied to understand their …
many vital body functions and should therefore be thoroughly studied to understand their …
Synthesis and immunological evaluation of disaccharide bearing MUC-1 glycopeptide conjugates with virus-like particles
X Wu, C McKay, C Pett, J Yu, M Schorlemer… - ACS chemical …, 2019 - ACS Publications
Mucin-1 (MUC1) is a highly attractive antigenic target for anticancer vaccines. Naturally
existing MUC1 can contain multiple types of O-linked glycans, including the Thomsen …
existing MUC1 can contain multiple types of O-linked glycans, including the Thomsen …
Total Synthesis of Pseudomonas aeruginosa 1244 Pilin Glycan via de Novo Synthesis of Pseudaminic Acid
H Liu, Y Zhang, R Wei, G Andolina… - Journal of the American …, 2017 - ACS Publications
Pseudaminic acid (Pse) is a nonulosonic acid unique to bacterial species, found as a
component of important cell surface glycans and glycoproteins in various pathogenic …
component of important cell surface glycans and glycoproteins in various pathogenic …
Synthesis and stereocontrolled equatorially selective glycosylation reactions of a pseudaminic acid donor: Importance of the side-chain conformation and …
Pseudaminic acid is an amino deoxy sialic acid whose glycosides are essential components
of many pathogenic Gram-negative bacterial cell walls including those from Pseudomonas …
of many pathogenic Gram-negative bacterial cell walls including those from Pseudomonas …
Growing impact of sialic acid-containing glycans in future drug discovery
In nature, almost all cells are covered with a complex array of glycan chain namely sialic
acids or nuraminic acids, a negatively charged nine carbon sugars which is considered for …
acids or nuraminic acids, a negatively charged nine carbon sugars which is considered for …
Recent progress on the chemical synthesis of bacterial non-2-ulosonic acids
X Guo, P Li, H Liu, X Li - Organic Chemistry Frontiers, 2023 - pubs.rsc.org
Bacteria resistant to antibiotics present a threat to public health. The bacterial non-2-
ulosonic acids, including pseudaminic acid, legionaminic acid, acinetaminic acid, fusaminic …
ulosonic acids, including pseudaminic acid, legionaminic acid, acinetaminic acid, fusaminic …