Background—The goal of this statement is to review available literature and to put forth a
scientific statement on the current practice of fetal cardiac medicine, including the diagnosis …

Effective screening for major aneuploidies can be provided in the first trimester of
pregnancy. Screening by a combination of fetal nuchal translucency and maternal serum …

Objective To examine the performance of the routine 11–13‐week scan in detecting fetal
non‐chromosomal abnormalities. Methods This was a retrospective study of prospectively …

Objective To examine the association between maternal age and a wide range of adverse
pregnancy outcomes after adjustment for confounding factors in obstetric history and …

Objectives To validate the clinical efficacy and practical feasibility of massively parallel
maternal plasma DNA sequencing to screen for fetal trisomy 21 among high risk …

Many doctors, patients, journalists, and politicians alike do not understand what health
statistics mean or draw wrong conclusions without noticing. Collective statistical illiteracy …

OBJECTIVE: We sought to assess performance of noninvasive prenatal testing for fetal
trisomy in a routinely screened first-trimester pregnancy population. STUDY DESIGN: This …

Objective To examine the performance of the 11–13 weeks scan in detecting non‐
chromosomal abnormalities. Methods Prospective first‐trimester screening study for …

Background It is uncertain how best to screen pregnant women for the presence of fetal
Down's syndrome: to perform first-trimester screening, to perform second-trimester …

There is extensive evidence that effective screening for major chromosomal abnormalities
can be provided in the first trimester of pregnancy. Prospective studies in a total of 200,868 …