Plants grow in dynamic environments where they can be exposed to a multitude of stressful
factors, all of which affect their development, yield, and, ultimately, reproductive success …

Acute stress puts cells at risk, and rapid adaptation is crucial for maximizing cell survival.
Cellular adaptation mechanisms include modification of certain aspects of cell physiology …

Poly (A) tails enhance the stability and translation of most eukaryotic messenger RNAs, but
difficulties in globally measuring poly (A)-tail lengths have impeded greater understanding of …

Cellular RNA levels are determined by the interplay of RNA production, processing and
degradation. However, because most studies of RNA regulation do not distinguish the …

Biological processes are often dynamic, thus researchers must monitor their activity at
multiple time points. The most abundant source of information regarding such dynamic …

The cytoplasmic abundance of mRNAs is strictly controlled through a balance of production
and degradation. Whereas the control of mRNA synthesis through transcription has been …

Maintaining proper mRNA levels is a key aspect in the regulation of gene expression. The
balance between mRNA synthesis and decay determines these levels. We demonstrate that …

To obtain rates of mRNA synthesis and decay in yeast, we established dynamic
transcriptome analysis (DTA). DTA combines non‐perturbing metabolic RNA labeling with …

The regulation of messenger RNA levels in mammalian cells can be achieved by the
modulation of synthesis and degradation rates. Metabolic RNA-labeling experiments in bulk …

The rates of mRNA synthesis and degradation determine cellular mRNA levels and can be
monitored by comparative dynamic transcriptome analysis (cDTA) that uses nonperturbing …