The functional diversity of protein lysine methylation

S Lanouette, V Mongeon, D Figeys… - Molecular systems …, 2014 - embopress.org
Large‐scale characterization of post‐translational modifications (PTM s), such as
phosphorylation, acetylation and ubiquitination, has highlighted their importance in the …

Enhancing the functional properties of thermophilic enzymes by chemical modification and immobilization

DA Cowan, R Fernandez-Lafuente - Enzyme and Microbial Technology, 2011 - Elsevier
The immobilization of proteins (mostly typically enzymes) onto solid supports is mature
technology and has been used successfully to enhance biocatalytic processes in a wide …

Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for antiviral defense …

NG Lintner, M Kerou, SK Brumfield, S Graham… - Journal of Biological …, 2011 - ASBMB
In response to viral infection, many prokaryotes incorporate fragments of virus-derived DNA
into loci called clustered regularly interspaced short palindromic repeats (CRISPRs). The …

Structure of the CRISPR interference complex CSM reveals key similarities with cascade

C Rouillon, M Zhou, J Zhang, A Politis… - Molecular cell, 2013 - cell.com
Summary The Clustered Regularly Interspaced Palindromic Repeats (CRISPR) system is an
adaptive immune system in prokaryotes. Interference complexes encoded by CRISPR …

Protein lysine methylation by seven-β-strand methyltransferases

PØ Falnes, ME Jakobsson, E Davydova… - Biochemical …, 2016 - portlandpress.com
Methylation of biomolecules is a frequent biochemical reaction within the cell, and a plethora
of highly specific methyltransferases (MTases) catalyse the transfer of a methyl group from S …

Functional differentiation determines the molecular basis of the symbiotic lifestyle of Ca. Nanohaloarchaeota

YG **e, ZH Luo, BZ Fang, JY Jiao, QJ **e, XR Cao… - Microbiome, 2022 - Springer
Abstract Background Candidatus Nanohaloarchaeota, an archaeal phylum within the
DPANN superphylum, is characterized by limited metabolic capabilities and limited …

The interplay between nucleoid organization and transcription in archaeal genomes

E Peeters, RPC Driessen, F Werner… - Nature Reviews …, 2015 - nature.com
The archaeal genome is organized by either eukaryotic-like histone proteins or bacterial-like
nucleoid-associated proteins. Recent studies have revealed novel insights into chromatin …

An exploration of aptamer internalization mechanisms and their applications in drug delivery

LY Wan, WF Yuan, WB Ai, YW Ai, JJ Wang… - Expert opinion on …, 2019 - Taylor & Francis
ABSTRACT Introduction: As 'chemical antibodies', aptamers have some advantages, such
as lack of immunogenicity, rapid tissue penetration, cell internalization and so on …

Utilizing proteomics to identify and optimize microalgae strains for high-quality dietary protein: A review

S Hamzelou, D Belobrajdic, JA Broadbent… - Critical Reviews in …, 2024 - Taylor & Francis
Algae-derived protein has immense potential to provide high-quality protein foods for the
expanding human population. To meet its potential, a broad range of scientific tools are …

Key concepts and challenges in archaeal transcription

F Blombach, D Matelska, T Fouqueau, G Cackett… - Journal of molecular …, 2019 - Elsevier
Transcription is enabled by RNA polymerase and general factors that allow its progress
through the transcription cycle by facilitating initiation, elongation and termination. The …